Results 41 to 50 of about 670,959 (215)
Refractivity of P2O5-Al2O3-SiO2 Glass in Optical Fibers
Photonics, 2023 A significant change in the refractive index profiles for the large mode area phosphoroaluminosilicate (PAS) core optical fibers was observed in comparison to that in preforms.
Mikhail E. Likhachev +7 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A Detailed Study of a Resonant-Assisted Segmented Cladding Fiber for Large Mode Area Applications
PhotonicsIn this work, we have proposed and optimized a large mode area segmented cladding fiber (SCF) with an unconventional low-index segment cladding. The low-refractive-index cladding proposed in this paper consists of three parts.
Minmin Xue +4 more
doaj +1 more source
Low-DMGD, Large-Effective-Area and Low-Bending-Loss 12-LP-Mode Fiber for Mode-Division-Multiplexing
IEEE Photonics Journal, 2019 We report the design of 12-LP-mode (21-spatial-mode) fiber with a low differential mode group delay (DMGD), a large effective area, and a low bending loss that is adapted to a mode-division-multiplexing system over the C+L band.
Huan Zhang +4 more
doaj +1 more source
Fabrication and Performance of a Heterogeneous-Helical-Cladding Fiber
IEEE Photonics Journal, 2021 Large mode area (LMA) fibers are widely used in high power fiber lasers to solve the nonlinear problems. In this work, a Nd3+-doped phosphate glass LMA fiber with heterogeneous helical claddings (HHC) is fabricated successfully by rod in tube ...
Xiao Shen +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Fibers, 2013 Large-size 0.1 Yb2O3–1.0 Al2O3–98.9 SiO2 (mol%) core glass was prepared by the sol–gel method. Its optical properties were evaluated. Both large mode area double cladding fiber (LMA DCF) with core diameter of 48 µm and large mode area photonic crystal ...
Shikai Wang +7 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source