Results 51 to 60 of about 9,501,678 (288)

A Neighborhood Search for Sequence-dependent Setup Time in Flow Shop Fabrics Making of Textile Industry [PDF]

, 2011
This paper proposes a neighborhood search to solve scheduling for fabrics making in a textile industry. The production process consists of three production stages from spinning, weaving, and dyeing. All stages have one processor.
Totong,, Kurniawan, Bobby, Sumihartati, Atin   +2 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modified ALNS Algorithm for a Processing Application of Family Tourist Route Planning: A Case Study of Buriram in Thailand

Computation, 2021
This research presents a solution to the family tourism route problem by considering daily time windows. To find the best solution for travel routing, the modified adaptive large neighborhood search (MALNS) method, using the four destructions and the ...
Narisara Khamsing, Kantimarn Chindaprasert, Rapeepan Pitakaso, Worapot Sirirak, Chalermchat Theeraviriya   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Solving Scheduling Problem in a Distributed Manufacturing System Using a Discrete Fruit Fly Optimization Algorithm

Energies, 2019
This study attempts to optimize the scheduling decision to save production cost (e.g., energy consumption) in a distributed manufacturing environment that comprises multiple distributed factories and where each factory has one flow shop with blocking ...
Xiaohui Zhang, Xinhua Liu, Shufeng Tang, Grzegorz Królczyk, Zhixiong Li   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A Learning Large Neighborhood Search for the Staff Rerostering Problem

, 2022
To effectively solve challenging staff rerostering problems, we propose to enhance a large neighborhood search (LNS) with a machine learning guided destroy operator. This operator uses a conditional generative model to identify variables that are promising to select and combines this with the use of a special sampling strategy to make the actual ...
Fabio Francisco Oberweger, Günther R. Raidl, Elina Rönnberg, Marc Huber   +3 more
openaire   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Multi-Port Stowage Planning for Inland Container Liner Shipping Considering Weight Uncertainties

IEEE Access, 2018
The multi-port stowage planning problem investigates the ship’s whole route to make the stowage plans for multiple ports. This paper formulates the multi-port stowage planning problem for inland container liner shipping on the Yangtze River that ...
Jun Li, Yu Zhang, Jie Ma, Sanyou Ji
doaj   +1 more source