Results 51 to 60 of about 10,004,845 (289)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres +6 more
wiley +1 more source
Flowchart of adaptive large neighborhood search algorithm.
, 2018 Flowchart of adaptive large neighborhood search algorithm.
Dezhi Zhang (3685177) +4 more
core +1 more source
Large Neighborhood Beam Search for Domain-Independent Dynamic Programming [PDF]
, 2023 Large neighborhood search (LNS) is an algorithmic framework that removes a part of a solution and performs search in the induced search space to find a better solution.
Beck, J. Christopher, Kuroiwa, Ryo
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A variable neighborhood-based heuristic for the heterogeneous fleet vehicle routing problem [PDF]
, 2008 The heterogeneous fleet vehicle routing problem is investigated using some adaptations of the variable neighborhood search (VNS). The initial solution is obtained by Dijkstra's algorithm based on a cost network constructed by the sweep algorithm and the ...
Imran, Arif +2 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Computation, 2021 This research presents a solution to the family tourism route problem by considering daily time windows. To find the best solution for travel routing, the modified adaptive large neighborhood search (MALNS) method, using the four destructions and the ...
Narisara Khamsing +4 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Energies, 2019 This study attempts to optimize the scheduling decision to save production cost (e.g., energy consumption) in a distributed manufacturing environment that comprises multiple distributed factories and where each factory has one flow shop with blocking ...
Xiaohui Zhang +4 more
doaj +1 more source