Results 61 to 70 of about 9,501,678 (288)

An Adaptive Large Neighborhood Search Algorithm for the Satellite Data Transmission Scheduling Problem

International Journal of Aerospace Engineering, 2020
Satellite establishes a satellite ground station to satellite link with a ground station to complete data transmission. However, in China, satellite ground stations only exist within the country.
Yingguo Chen, Ming Chen, Jun Wen, Yingwu Chen, Wen Xiang   +4 more
doaj   +1 more source

Asymmetric Arc Routing by Coordinating a Truck and Multiple Drones

Sensors, 2022
Unmanned Aerial Vehicles, commonly known as drones, have been widely used in transmission line inspection and traffic patrolling due to their flexibility and environmental adaptability.
Shuangxi Tian, Honghui Chen, Guohua Wu, Jiaqi Cheng   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

An Improved Large Neighborhood Search for Network-Level Airport Slot Allocation Optimization

IEEE Access
Airports worldwide face a significant gap between capacity and demand. As a short-term solution, the International Air Transport Association has implemented schedule coordination rules at busy airports.
Qiangzhe Wang, Yuanyuan Ma, Yifan Xu, Zhiyuan Shen, Dan Li   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Adaptive Large Neighborhood Search for a Production Planning Problem Arising in Pig Farming

Journal of Open Innovation: Technology, Market and Complexity, 2019
. This article aims to resolve a particular production planning and workforce assignment problem. Many production lines may have different production capacities while producing the same product. Each production line is composed of three production stages,
Nat Praseeratasang, Rapeepan Pitakaso, Kanchana Sethanan, Sasitorn Kaewman, Paulina Golinska-Dawson   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Terrain-Adaptive Global Path Planning Method Based on Bidirectional Variable Neighborhood Search A*

Actuators
To address the issues of low efficiency and non-smooth paths of the A* algorithm in large-scale environments, a terrain-adaptive global path planning method based on Bidirectional Variable Neighborhood Search A* (Terrain-Adaptive Bidirectional Variable ...
Ze Zhang, Ke Liu, Yulong Lei, Yao Fu, Yutong Liu   +4 more
doaj   +1 more source