Results 61 to 70 of about 28,703 (294)

Large strain consolidation of dredged slurries considering clogging effect with coupled vertical–radial flow

open access: yes, 2023
Dredged slurries improved by vacuum preloading methods were found to be still weak generally after the pore water drainage finished. Three reasons, including nonuniform consolidation, soil particles migration and blockage of the drain filter, have been ...
Cai, Yuanqiang   +6 more
core   +1 more source

Three-dimensional large-strain consolidation considering creep behavior improved by vacuum preloading

open access: yesYantu gongcheng xuebao
The creep settlement in deep soft soil during consolidation is significant, rendering the classical small-strain consolidation theory inadequate. A three-dimensional large-deformation consolidation theory is proposed for soft soil under vacuum loading ...
ZHOU You 1, 2 , GUO Wei 1, 2, REN Yuxiao 1, 2, ZHANG Qizheng 1, 2
doaj   +1 more source

Experimental study on dynamic deformation behavior of rockfill materials

open access: yesYantu gongcheng xuebao, 2018
Large-scale cyclic simple shear tests on rockfill materials of limestone are performed to study the characteristics of dynamic moduli, damping ratios and residual deformations.
LÜ Xiao-long 1, 2, CHI Shi-chun 1,2, JIA Yu-feng 1, 2
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Causes of post-installation penetration of jack-up spudcan foundations in clays.

open access: yesPLoS ONE, 2018
This paper examines possible causes of additional spudcan settlement after preloading using both centrifuge model tests and small strain finite element analysis, in which spudcan settlement due to cavity collapse, consolidation settlement and settlement ...
Yu Ping Li   +6 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

A FDM Solving Method of Large-Strain Consolidation of Multi-Layers Super Soft-Soil

open access: yes, 2011
The aim is to present a numerical method to solve the large-strain consolidation of super soft-soil. The theory of large-strain consolidation (LSC) is acted as the better method for analysis on the consolidation problem of super soft-soil foundation. The
Jia Lan Zhang, Hai Jia Wen
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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