Results 101 to 110 of about 15,790,105 (302)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structure and function of the large intestine (nursing students)

open access: yes, 2010
This topic describes the structure and function of the various parts of the large intestine, including the appendix, caecum, colon (ascending, descending, transverse and sigmoid), rectum and anal canal.
Raja Habib   +1 more
core  

Model tests on disturbance characteristics of surrounding rock of loess shield tunnels during excavation

open access: yesYantu gongcheng xuebao
In order to explore the disturbance characteristics of the surrounding rock by excavation of loess shield tunnels under different water contents and buried depths, the similarity model tests are carried out.
HAN Xingbo 1, 2, CHEN Ziming 1, YE Fei 1, 2, LIANG Xiaoming 3, FENG Haolan 1, XIA Tianhan 1
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Large structure control development concepts [PDF]

open access: yes, 1978
Viewpoints are presented on large structure control evolving from the solar sail study conducted at JPL. The objective is to make optimum use of insights gained in the study in order to assess required large structure control ...
Rodriguez, G.
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Structure of Complex, Large-scale Governance Systems

open access: yes, 2018
Large-scale governance systems can be considered complex systems. They encompass organizations involved in a multitude of substantive issues, on various jurisdictional levels and in different phases of the policy process. General complexity theory posits
Angst, Mario
core  

Large intermixing in the InGaP/InAlGaP laser structure using stress engineering at elevated temperature

open access: yes, 2019
In this paper, a thermally induced dielectric strain on quantum well intermixing (QWI) technique is employed on tensilestrained InGaP/InAlGaP laser structure, to promote inter-diffusion, in conjunction with cycle annealing at elevated temperature.
Shehata, Mohamed   +15 more
core   +1 more source

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