Results 101 to 110 of about 2,779,394 (268)

Euclid preparation

open access: yesAstronomy & Astrophysics
We investigated the accuracy and range of validity of the perturbative model for the two-point (2PCF) and three-point (3PCF) correlation functions in real space in view of the forthcoming analysis of the Euclid mission spectroscopic sample.
Guidi M.   +309 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Radio-loudness Statistics of Quasars from Quaia-VLASS

open access: yesThe Astrophysical Journal Supplement Series
Quasars are objects of high interest in extragalactic astrophysics, cosmology, and astrometry. One of their useful qualities is their potential radio-loudness.
Nestor Arsenov   +3 more
doaj   +1 more source

The role of energy shear in the collapse of protohaloes

open access: yesAstronomy & Astrophysics
Dark matter haloes form from the collapse of matter around special positions in the initial field, those where the local matter flows converge to a point. For such a triaxial collapse to take place, the energy shear tensor (the source of the evolution of
Musso Marcello, Sheth Ravi K.
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Galaxy transformation across the cosmic web: The influence zone of filaments

open access: yesAstronomy & Astrophysics
Context. The matter distribution in the Universe exhibits a rich variety of structures, and they form the so-called cosmic web. These structures arise from the anisotropic gravitational collapse of primordial density fluctuations and define the pathways ...
Alfonso L. Aguerri J., Zarattini Stefano
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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