Results 81 to 90 of about 15,790,105 (302)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Large-scale structure observations [PDF]

open access: yes, 2015
Lectures given at Post-Planck Cosmology, Ecole de Physique des Houches, Les Houches, July 8-Aug 2, 2013, eds. B. Wandelt, C. Deffayet, P. Peter, to be published by Oxford University Press, and New Horizons for Observational Cosmology, International School of Physics Enrico Fermi, Varenna, July 1-6, 2013, eds. A. Melchiorri, A. Cooray, E. Komatsu, to be
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Modelling and design of a coupled system of multiple hydraulic systems and large structures

open access: yesNihon Kikai Gakkai ronbunshu
Control of large structures often involves the use of hydraulic equipment due to the large power requirements. In this study, a large telescope is taken as an example of a large structure.
Tomoya HATTORI   +2 more
doaj   +1 more source

The Large Space of Information Structures

open access: yes, 2019
We revisit the question of modeling incomplete information among 2 Bayesian players, following an ex-ante approach based on values of zero-sum games. $K$ being the finite set of possible parameters, an information structure is defined as a probability distribution $u$ with finite support over $K\times \mathbb{N} \times \mathbb{N}$ with the ...
Gensbittel, Fabien   +2 more
openaire   +3 more sources

Interpretation of large-scale spiral structure [PDF]

open access: yesSymposium - International Astronomical Union, 1970
The present paper consists of three parts: (1) A general explanation, from a semi-empirical point of view, of the density wave theory and its ramifications, with only a few remarks on those detailed features which have not been stressed before; (2) a statement of our conclusions about the Milky Way System; and (3) a discussion of the problem of the ...
openaire   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Large-Scale Category Structure Aware Image Categorization

open access: yes, 2018
Most previous research on image categorization has focused on medium-scale data sets, while large-scale image categorization with millions of images from thousands of categories remains a challenge.
Bin Zhou (5364197)   +2 more
core   +1 more source

Revisiting the angular size–redshift cosmological test with milliarcsecond radio structures in active galactic nuclei

open access: yesAstronomy & Astrophysics
Context. Very long baseline interferometry (VLBI) measurements of the sizes of compact extragalactic radio sources, jetted active galactic nuclei, provide data for probing the angular size–redshift relation, offering a classical cosmological test ...
Ghodsi Yengejeh Mina   +7 more
doaj   +1 more source

The Large-Scale Structure of the Universe [PDF]

open access: yes, 2013
Galaxies are not uniformly distributed in space. On large scales the Universe displays coherent structure, with galaxies residing in groups and clusters on scales of ~1-3 Mpc/h, which lie at the intersections of long filaments of galaxies that are >10 Mpc/h in length.
openaire   +2 more sources

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