Establishment of RPA-CRISPR/Cas12a Detection Methods for Rapid Largemouth Bass Ranavirus Surveillance [PDF]
The high mortality associated with largemouth bass ranavirus (LMBRaV) disease requires rapid and sensitive diagnosis methods to prevent virus spread and subsequent outbreak. The recombinase polymerase amplification combined with the CRISPR/Cas12a system (
Haoyu Wang +11 more
doaj +2 more sources
Preparation and Efficacy Evaluation of Heat-Resistant Freeze-Dried Live-Attenuated Vaccine Formulation of Micropterus salmoides Rhabdovirus [PDF]
Background/Objectives: An attenuated strain of Micropterus salmoides rhabdovirus (MSRV) 0509 with good immunogenicity has been isolated, showing potential as a candidate for live vaccine development.
Hongru Liang +9 more
doaj +2 more sources
Hiding in Plain Sight: Genomic Characterization of a Novel Nackednavirus and Evidence of Diverse Adomaviruses in a Hyperpigmented Lesion of a Largemouth Bass (Micropterus nigricans) [PDF]
Largemouth bass (LMB; Micropterus nigricans) are popular both as a sportfish and an aquaculture species. At present, six described viruses are associated with LMB, of which two are typically considered in cases of LMB mortality events.
Clayton Raines +5 more
doaj +2 more sources
Newly discovered and conserved role of IgM against viral infection in an early vertebrate [PDF]
IgM emerged in jawed vertebrates 500 Mya and remains the most evolutionarily conserved antibody class. However, despite extensive studies on IgM as an ancient antiviral weapon in warm-blooded vertebrates, its role and mechanisms in combating viral ...
Weiguang Kong +9 more
doaj +2 more sources
Immunoglobulin M response in largemouth bass (Micropterus salmoides) following ranavirus infection [PDF]
Immunoglobulin M (IgM) and IgM+ B cells are key components of the humoral immune system, providing defense against pathogen invasion. While the role of IgM in the systemic and mucosal immune responses of fish to parasites and bacteria has been partially ...
Zhenyu Huang +10 more
doaj +2 more sources
The largemouth bass is a freshwater aquacultured fish species of great economic importance in China. With the rapid development of aquaculture industry and the increase in the aquaculture density of the fish, various infectious pathogens, including ...
Yi-Fan Zhang +7 more
doaj +2 more sources
Immunological Responses and Protection in the Largemouth Bass (Microterus salmoides) Immunized with Inactivated Vaccine Against Largemouth Bass Ranavirus (LMBRaV) [PDF]
The largemouth bass ranavirus (LMBRaV) caused significant mortality and economic loss in the largemouth bass aquaculture industry around the world, including China. Vaccination is an efficient method for virus defense.
Tao Yang +10 more
doaj +2 more sources
Identification and characterization of a novel orthoreovirus from American eels, Anguilla rostrata [PDF]
Hemorrhagic gill necrosis disease (HGND) has resulted in substantial economic losses in the farming of American eels (Anguilla rostrata). Although prior research implicates viruses like American eel adomavirus (AEAdoV) and Anguillid herpesvirus (AngHV ...
Jin-Xian Yang +4 more
doaj +2 more sources
Multi-omics analysis reveals that Bacillus spp. enhance mucosal antiviral immunity in teleost fish by mediating diglyceride production through lipid metabolism [PDF]
Background Symbiotic microbiota in vertebrates play critical roles in establishing and enhancing host resistance to pathogenic infections as well as maintaining host homeostasis.
Gaofeng Cheng +10 more
doaj +2 more sources
A subunit vaccine of largemouth bass (Micropterus salmoides) with baculovirus-expressed largemouth bass ranavirus (LMBRaV) major capsid protein induces protective immunity against LMBRaV infection [PDF]
Largemouth Bass Ranavirus (LMBRaV) is associated with large mortalities of farmed Largemouth Bass (Micropterus salmoides), which has caused huge economic loss to its aquaculture in China.
Yiqun Li +11 more
doaj +2 more sources

