Results 111 to 120 of about 4,378 (208)

Efficacy of larotrectinib in pediatric cancers with <i>NTRK</i> gene fusions. [PDF]

Transl Pediatr
Houghton PJ, Bjornsti MA.
europepmc   +1 more source

Advancing the treatment of NTRK-fused pediatric solid tumors: lessons from the ADVL1823 study. [PDF]

Transl Pediatr
Vince CSC, Valera ET.
europepmc   +1 more source

JOSHA’S CRITICAL REVIEW OF “ Efficacy of Larotrectinib in TRK Fusion– Positive Cancers in Adults and Children

, 2018
Roland Mertelsmann, Gerhard Steinmann
openalex   +2 more sources

Current therapeutic landscape and resistance mechanisms to larotrectinib

Cancer Biology & Medicine, 2023
Weiji Xie, Jiaqian Xu, Suying Lu, Yizhuo Zhang   +3 more
doaj   +1 more source

Clinicopathologic and molecular spectrum of gastrointestinal stromal tumor (GIST) with NTRK fusion and marked response to larotrectinib in GIST with NTRK fusion: a case report. [PDF]

Cell Oncol (Dordr)
Shen Y, Peng Q, Wen J, Yang L, Zhu L, Chen Y, Liu Q, Wang L, Yao J, Li A, Wang M, Liu Z.   +11 more
europepmc   +1 more source

TPM3-NTRK1 Fusion Cervical Sarcoma: A Case Report of a Novel Subset of Gynaecological Sarcomas and Successful Treatment of Recurrent Disease With Trk-Inhibition Therapy. [PDF]

Cureus
Lowe-Zinola J, Elghobashy M, Evans M, Hafeez T, El-Ghobashy A.   +4 more
europepmc   +1 more source

Comprehensive characterization and targeted treatment of a pediatric epithelioid glioblastoma with a rare TRIM24-NTRK2 fusion. [PDF]

NPJ Precis Oncol
Keane S, Sjöberg I, Deland L, Lindlöf A, Bontell TO, Kling T, Blomstrand M, Fagman H, Nilsson JA, Nilsson D, Sabel M, Carén H, Abel F.   +12 more
europepmc   +1 more source

Larotrectinib Demonstrates CNS Efficacy in TRK Fusion-Positive Solid Tumors

, 2019
Ezra Y. Rosen, Alison M. Schram, Robert J. Young, Mark Schreyer, Jaclyn F. Hechtman, Catherine A. Shu, Nora Ku, David M. Hyman, Alexander Drilon   +8 more
openalex   +1 more source

Phase 1/2 study of the selective TRK inhibitor larotrectinib, in pediatric patients with cancer [PDF]

, 2017
Soledad Gallego, Michela Casanova, Stefan Bielack, Julia Chisholm, C.S. van Tilburg, Noah Federman, Catherine M. Albert, Leo Mascarenhas, Brian Turpin, Ramamoorthy Nagasubramanian, Neerav Shukla, Sheri L. Spunt, M.C. Cox, Douglas S. Hawkins, Alberto S. Pappo, François Doz, Gianni Bisogno, Steven G. DuBois, Theodore W. Laetsch, Birgit Geoerger   +19 more
openalex   +1 more source

Neurotrophin NGF/TrkA and BDNF/TrkB signaling orchestrates the immune microenvironment in osteosarcoma. [PDF]

Front Immunol
Liu H, Wang G, Wang C, Hou D, Li S, Fan Y, Liu B.   +6 more
europepmc   +1 more source