Results 41 to 50 of about 1,211 (176)

The RNA-binding protein LARP1 is dispensable for pancreatic β-cell function and mass

Scientific Reports, 2021
Mechanistic target of rapamycin complex 1 (mTORC1) deficiency or chronic hyperactivation in pancreatic β-cells leads to diabetes. mTORC1 complexes with La-related protein 1 (LARP1) to specifically regulate the expression of 5′ terminal oligopyrimidine ...
Joao Pedro Werneck-de-Castro, Flavia Leticia Martins Peçanha, Diego Henrique Silvestre, Ernesto Bernal-Mizrachi   +3 more
doaj   +1 more source

Co‐translational protein targeting to mitochondria in the context of co‐translational protein maturation

Protein Science, Volume 35, Issue 7, July 2026.
Abstract Mitochondria import the majority of their proteins from the cytosol, creating a fundamental challenge: precursor proteins must be synthesized, maintained in an import‐competent state, and delivered to mitochondrial translocases without premature folding or aggregation. While mitochondrial protein import has been considered a post‐translational
Nikita A. Kvasov, Yury S. Bykov
wiley   +1 more source

An examination of living through enjoyment: Live-action role-play

Transformative Works and Cultures, 2009
Many in the gaming community argue that video gaming has enhanced the RPG experience, allowing for ever more immersive experiences for players. The live-action aspects of LARPing anticipated the movement toward virtual play that video games have worked ...
Amanda Odom
doaj   +1 more source

‘It's Like a Horror Movie That You Walk Through’: Experiencing Horror Through Immersive Recreation

The Journal of American Culture, Volume 49, Issue 2, Page 121-130, June 2026.
ABSTRACT Horror stories have provided enjoyable forms of leisure for centuries. Over the past five decades, however, these experiences have evolved into increasingly immersive forms of popular culture. What once involved constructing the narrative world internally through reading has expanded into sensory engagement through visual and auditory media ...
Susan Weidmann
wiley   +1 more source

Spatiotemporal Contaminant Occurrence and Risk Assessment in the Arroio Dourado River Under the Influence of Agriculture and a Deactivated Dumpsite

Water Environment Research, Volume 98, Issue 5, May 2026.
Integrated monitoring and risk assessment of an agricultural river influenced by a deactivated dumpsite. ABSTRACT This study evaluated the impacts of agricultural activities and a decommissioned landfill on the Arroio Dourado River and identified critical sampling periods and strategic monitoring locations.
Marcela Boroski, Sílvia Sônia da Silva, Lizandra Martins Soares, Kleber Gomes Ramirez, Fernanda Rubio, Jiam Pires Frigo, Luiz Henrique Garcia Pereira, Paula Fernandes de Aguiar, Carla Sirtori   +8 more
wiley   +1 more source

What Supports and Constrains the Implementation of Robust and Rapid Evaluation Within Local Government Public Health Systems?

Health Expectations, Volume 29, Issue 2, April 2026.
ABSTRACT Background Since 2013, local government in England has held statutory responsibility for public health and concurrently faced financial pressures and limited research capacity. The National Institute of Health and Care Research (NIHR) established Public Health Intervention Responsive Studies Teams (PHIRST) to bridge this gap, commissioning ...
Gemma Bridge, Jane Wills, Jessica T. Oha, Thomas Mills, Apolonia Radomska, Susie Sykes   +5 more
wiley   +1 more source

Highly Fluorescent and Stable Lead Halide Perovskite Nanocrystals Protected by an In Situ Formed Lead Halide–Amino Acid Matrix

Advanced Photonics Research, Volume 7, Issue 3, March 2026.
This work presents highly fluorescent and stable MAPbBr3 and FAPbBr3 perovskite nanocrystals prepared via a facile single‐step precipitation method. An in situ formed PbBr2­amino acid matrix encapsulates the nanocrystals, enabling near‐unity photoluminescence quantum yields and exceptional long‐term stability under ambient conditions.
Felix Mayr, Elisabeth Leeb, Katharina Matura, Munise Cobet, Thomas Rath, Marco Sigl, Yolanda Salinas, Dorian Ziss, Tena Markulin, Jakob Hofinger, Katarina Gugujonović, Bekele Hailegnaw, Oliver Brüggemann, Thomas A. Klar, Niyazi S. Sariciftci, Markus C. Scharber   +15 more
wiley   +1 more source

Titiller la fiction historique d’un jeu

Sciences du Jeu, 2023
Representations of the past are often used in the fiction of board games and video games. What happens to historical content when people play with it? This article draws on ethnographic data from an observational participation in Legion: Siberian Story ...
Michael Freudenthal
doaj   +1 more source

Recent Advances in Quantum Dots‐Based Sensors for the Detection of Tuberculosis: A Review

ChemistrySelect, Volume 11, Issue 6, 12 February 2026.
Quantum dot‐based biosensors enable rapid, sensitive detection of tuberculosis by converting biomolecular interactions into fluorescent signals. Target‐specific probes recognize TB biomarkers, producing measurable optical responses. This platform offers high sensitivity, multiplexing capability, and portability, supporting early diagnosis and improved ...
Alungile Mtotywa, Siyasanga Booysen, Mduduzi P. Radebe, Fredrick O. Okumu, Bernard O. Owaga, Martin O. Onani   +5 more
wiley   +1 more source

An examination of living through enjoyment: Live-action role-play [symposium]

Transformative Works and Cultures, 2009
Many in the gaming community argue that video gaming has enhanced the RPG experience, allowing for increasingly immersive experiences for players. The live-action aspects of LARPing anticipated the movement toward virtual play that video games have ...
Amanda Odom
doaj   +1 more source