Results 41 to 50 of about 60,818 (294)

Tapered amplifier laser with frequency-shifted feedback

open access: yesSciPost Physics, 2016
We present a frequency-shifted feedback (FSF) laser based on a tapered amplifier. The laser operates as a coherent broadband source with up to 370GHz spectral width and 2.3us coherence time.
A. Bayerle, S. Tzanova, P. Vlaar, B. Pasquiou, F. Schreck
doaj   +1 more source

Integrated Phase-locked Laser Diodes at 1.55μm [PDF]

open access: yes, 2017
Two types of integrated phased locked laser diodes operating at 1.55 μm were demonstrated, using either a distributed feedback laser seeding source or a self-locking multi-mode interference array.
Hou, Lianping   +2 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Few-cycle Yb-doped laser sources for attosecond science and strong-field physics

open access: yesAPL Photonics
Yb-doped laser amplifiers have, in recent years, found applications in attosecond science, driven largely by the opportunities associated with high-average-power and high-repetition-rate attosecond sources.
Tran-Chau Truong   +4 more
doaj   +1 more source

Compact Aberration-Free Relay-Imaging Multi-Pass Layouts for High-Energy Laser Amplifiers

open access: yesApplied Sciences, 2016
We present the results from a theoretical investigation of laser beam propagation in relay imaging multi-pass layouts, which recently found application in high-energy laser amplifiers.
Jörg Körner   +2 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Inhomogeneous Gain Saturation in EDF: Experiment and Modeling

open access: yes, 2011
Erbium-Doped Fiber Amplifiers can present holes in spectral gain in Wavelength Division Multiplexing operation. The origin of this inhomogeneous saturation behavior is still a subject of controversy.
Boivin, David   +4 more
core   +1 more source

Ion-Exchanged Glass Waveguide Technology: A Review [PDF]

open access: yes, 2011
We review the history and current status of ion exchanged glass waveguide technology. The background of ion exchange in glass and key developments in the first years of research are briefly described.
Honkanen, Seppo   +2 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Polarization-independent wavelength conversion at 2.5 Gb/s by dual-pump four-wave mixing in a strained semiconductor optical amplifier [PDF]

open access: yes, 1996
We give a general expression for the polarization dependence of the four-wave mixing (FWM) efficiency in the dual-pump configuration. This expression, along with some general properties of the FWM susceptibility tensor, is used to propose a simple scheme
Geraghty, David F.   +4 more
core   +1 more source

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