Results 51 to 60 of about 60,955 (295)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Wavelength-Tunable Chirped Pulse Amplification System (1720 nm–1800 nm) Based on Thulium-Doped Fiber

open access: yesPhotonics
Chirped pulse amplification (CPA) has been a commonly used methodology to obtain powerful ultrashort laser pulses ever since its first demonstration. However, wavelength-tunable CPA systems are much less common.
Xinyang Liu, Regina Gumenyuk
doaj   +1 more source

Passive alignment stability and auto-alignment of multipass amplifiers based on Fourier transforms

open access: yes, 2019
The stability properties of Fourier-based multipass amplifier to misalignments (tilts) of its optical components has been investigated. For this purpose, a method to quantify the sensitivity to tilts based on the amplifier small signal gain has been ...
Antognini, Aldo   +10 more
core   +3 more sources

Wavelength conversion at 10 Gb/s by four-wave mixing over a 30-nm interval [PDF]

open access: yes, 1998
We show that the use of a long semiconductor optical amplifier increases the error-free conversion interval of a four-wave mixing (FWM)-based wavelength converter.
D'Ottavi, A.   +6 more
core   +1 more source

Optical fibres, lasers, and amplifiers [PDF]

open access: yesEndeavour, 1992
Initially, the only operation that could be performed in optical fibre communication was transmitting optical information from one point to another, necessitating complex auxiliary electronic circuitry. In recent years, however, a range of fibre components has been developed which promise to become as ubiquitous and indispensable as the transistor is ...
openaire   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Self-injection-locked thin-film regenerative laser amplifier

open access: yesiScience
Summary: Organic lasers based on distributed feedback (DFB) microcavities have been extensively investigated. However, the application of these lasers is limited by their low output power and large beam divergence.
Yue Liu, Wenwen Wu, Xinping Zhang
doaj   +1 more source

High-Power, Wavelength-Locked 878.6 nm In-Band Pumped, Acoustic-Optically Q-Switched Nd:YVO4 MOPA Laser With TEM00 Mode

open access: yesIEEE Photonics Journal, 2016
In this paper, a wavelength-locked 878.6-nm pumped acoustic-optically Q-switched Nd:YVO4 laser is presented. A master oscillator power amplifier configuration with two-stage amplifiers is employed to scale the output power.
Qiang Liu   +3 more
doaj   +1 more source

Transient dynamics of linear quantum amplifiers [PDF]

open access: yes, 2004
The transient dynamics of a quantum linear amplifier during the transition from damping to amplification regime is studied. The master equation for the quantized mode of the field is solved, and the solution is used to describe the statistics of the ...
14   +16 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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