Results 91 to 100 of about 253,283 (318)

Effective Technique Using Combined CO2 Laser and Pulsed Dye Laser for Facial Angiofibromas Management in Tuberous Sclerosis

Case Reports in Dermatological Medicine
Background. Facial angiofibromas (FAs) are a dermatological characteristic which are typically linked to tuberous sclerosis (TS). Aim. We discuss our experience, highlighting a rare occurrence of multiple FAs in a young patient, successfully treated with
Giuseppe Lodi, Giovanni Cannarozzo, Irene Fusco, Tiziano Zingoni, Elena Campione, Mario Sannino   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Bio-optimized energy transfer in densely packed fluorescent protein enables near-maximal luminescence and solid-state lasers [PDF]

, 2014
This work was supported by the US National Science Foundation (ECCS- 1101947), National Institutes of Health (P41EB015903, R21EB013761), Department of Defense (FA9550-11-1-0331), and the Korea National Research Foundation (R31-2008-000-10071-0).
Gather, Malte Christian, Yun, Seok Hyun
core   +1 more source

Terahertz Time-Domain Spectroscopy Materials Parameters Extraction Using Neural Networks [PDF]

EPJ Web of Conferences
In this work, we present a novel approach to determine the refractive index n and the extinction coefficient κ from terahertz time-domain spectroscopy (THz-TDS) measurements using artificial neural networks (ANNs).
Kaouther Cherigui Amina, Lazoul Mohamed
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Characterization of wavelength tunable lasers for future optical communication systems [PDF]

, 2010
The use of tunable lasers (TL) in dense wavelength division multiplexed (DWDM) networks for optical switching, routing and networking has gained a lot of interest in recent years.
Anandarajah, Prince M., Barry, Liam P., Shi, Kai, Kaszubowska-Anandarajah, Aleksandra, Maher, Robert D.   +4 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Characteristics of Q-switched cladding-pumped ytterbium-doped fiber lasers with different high-energy fiber designs [PDF]

, 2001
We theoretically and experimentally analyze Q-switched cladding pumped ytterbium-doped fiber lasers designed for high pulse energies. We compare the extractable energy from two high-energy fiber designs: (1) single- or few-moded low-NA large mode area ...
Alvarez-Chavez, J.A., Clarkson, W.A., Nilsson, J., Offerhaus, H.L., Turner, P.W., Renaud, Cyril C., Richardson, D.J., Grudinin, A.B.   +7 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Linewidth and phase noise characteristics of DFB fibre lasers [PDF]

, 2004
The anomalous linewidth behavior in a DFB fiber laser is investigated. It is shown that not only does the linewidth deviate drastically from the Schawlow-Townes linewidth formula by increasing with pump and laser power, but it also varies significantly ...
Voo, N.Y., Horak, P., Morten Ibsen, N. Y. Voo, Ibsen, M., Peter Horak, Wei H. Loh, Loh, W.H.   +7 more
core   +1 more source