Results 81 to 90 of about 322,270 (296)

Mammalian cell sensitivity to hyperthermia in various cell lines: a new universal and predictive description

International Journal of Hyperthermia, 2020
Introduction The Cumulative Equivalent Minute at 43 °C (CEM43) thermal dose model has been empirically derived more than 30 years ago and still serves as a benchmark for hyperthermia protocols despite the advent of regulatory network models.
D. Labavić, M. T. Ladjimi, E. Courtade, B. Pfeuty, Q. Thommen   +4 more
doaj   +1 more source

Transform-limited dual-comb spectroscopy using free-running waveguide lasers

, 2017
We present a standalone dual-comb platform based on two mutually stable waveguide lasers integrated in the same glass chip. Residual fluctuations are compensated using an algorithm seeded only by interferograms, which yields transform-limited ...
Lancaster, D.G., Nicolas Bourbeau Hébert, Genest, J., Khurmi, C., George Y. Chen, Hébert, N.B., David G. Lancaster, Deschênes, J.D., Jérôme Genest, Jean-Daniel Deschênes, Bergeron, H., Hugo Bergeron, Champak Khurmi, Chen, G.Y.   +13 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The fabrication and lithography of conjugated polymer distributed feedback lasers and development of their applications [PDF]

, 2007
This thesis presents a study of lasing properties and optical amplification in semiconducting conjugated polymers and dendrimers. Configured as surface-emitting distributed feedback lasers, the effect of incorporating wavelength-scale microstructure on ...
Richardson, Scott
core   +2 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Bio-optimized energy transfer in densely packed fluorescent protein enables near-maximal luminescence and solid-state lasers [PDF]

, 2014
This work was supported by the US National Science Foundation (ECCS- 1101947), National Institutes of Health (P41EB015903, R21EB013761), Department of Defense (FA9550-11-1-0331), and the Korea National Research Foundation (R31-2008-000-10071-0).
Gather, Malte Christian, Yun, Seok Hyun, Gather, Malte Christian; id_orcid   +2 more
core   +1 more source

Integrated Modelocked Comb Lasers for Spectroscopy Applications

, 2022
Paper W2F.4We present our work on the realization of integrated III/V-on-silicon integrated mode-locked lasers.
Roelkens, G., Uvin, S., Bente, E., Keyvaninia, S., Kuyken, B., Gasse, K. van, Latkowski, S., Wang, Z.   +7 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Terahertz Time-Domain Spectroscopy Materials Parameters Extraction Using Neural Networks [PDF]

EPJ Web of Conferences
In this work, we present a novel approach to determine the refractive index n and the extinction coefficient κ from terahertz time-domain spectroscopy (THz-TDS) measurements using artificial neural networks (ANNs).
Kaouther Cherigui Amina, Lazoul Mohamed
doaj   +1 more source