Results 11 to 20 of about 13,667 (181)
Viruses, 2012 Lassa virus, an Old World arenavirus (family Arenaviridae), is the etiological agent of Lassa fever, a severe human disease that is reported in more than 100,000 patients annually in the endemic regions of West Africa with mortality rates for ...
David H. Walker, Nadezhda E. Yun
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Development of a new vaccine for the prevention of Lassa fever.
PLoS Medicine, 2005 BACKGROUND: Recent importation of Lassa fever into Germany, the Netherlands, the United Kingdom, and the United States by travelers on commercial airlines from Africa underscores the public health challenge of emerging viruses.
Thomas W Geisbert +15 more
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Detection of Lassa Virus, Mali [PDF]
Emerging Infectious Diseases, 2010 To determine whether Lassa virus was circulating in southern Mali, we tested samples from small mammals from 3 villages, including Soromba, where in 2009 a British citizen probably contracted a lethal Lassa virus infection.
David Safronetz +10 more
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Comparative studies on Mopeia viruses and other Arenaviridae, particularly Lassa virus [PDF]
, 1983 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Serologically related arenaviruses have been isolated from West Africa, Mozambique, Zimbabwe and the Central African Republic.
Lloyd, Graham
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Space-Time Trends in Lassa Fever in Sierra Leone by ELISA Serostatus, 2012–2019
Microorganisms, 2021 Lassa fever (LF) is a viral hemorrhagic disease found in Sub-Saharan Africa and is responsible for up to 300,000 cases and 5000 deaths annually. LF is highly endemic in Sierra Leone, particularly in its Eastern Province.
Jeffrey G. Shaffer +19 more
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Molecular Therapy: Oncolytics, 2021 The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using established ...
Teddy E. Kim +8 more
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PLoS Neglected Tropical Diseases, 2022 IntroductionLassa virus is a priority pathogen for vaccine research and development, however the duration of cellular immunity and protection in Lassa fever (LF) survivors remains unclear.MethodsWe investigated Lassa virus specific CD8+ T cell responses ...
Stephanie M LaVergne +10 more
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Analysis of Determinants in Filovirus Glycoproteins Required for Tetherin Antagonism
Viruses, 2014 The host cell protein tetherin can restrict the release of enveloped viruses from infected cells. The HIV-1 protein Vpu counteracts tetherin by removing it from the site of viral budding, the plasma membrane, and this process depends on specific ...
Kerstin Gnirß +7 more
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Challenges and Opportunities in Lassa fever Control Efforts in Nigeria
The Proceedings of the Nigerian Academy of Science, 2022 Lassa fever is a viral zoonotic tropical disease endemic in parts of West Africa. It causes substantial mortality, morbidity and economic burdens on affected populations.
Anise N. Happi +3 more
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A GIS-BASED APPROACH TO RISK MAPPING OF LASSA FEVER OUTBREAK IN AKURE SOUTH LOCAL GOVERNMENT AREA, NIGERIA [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2022 Lassa fever is an acute viral illness, which is endemic in some counties in West Africa, including Guinea, Liberia, Sierra Leone and parts of Nigeria.
O. J. Ifejube +3 more
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