Results 71 to 80 of about 9,289 (204)

Retrospective Study on Liberation in Dogs Undergoing Mechanical Ventilation for Longer Than 24 Hours

Journal of Veterinary Emergency and Critical Care, Volume 36, Issue 2, Page 235-247, March/April 2026.
ABSTRACT Objective To describe liberation in a population of dogs undergoing ≥24 h of mechanical ventilation (MV) and to assess for differences between successful and unsuccessful liberation attempts as well as adherence to criteria for veterinary and human readiness to discontinue MV. Design Retrospective study.
Abigail E. McNally, Thomas D. Greensmith, Stefano Cortellini   +2 more
wiley   +1 more source

Structural and functional studies of novel mechanisms of Lassa fever virus nucleoprotein in immune suppression, viral RNA transcription and replication

, 2013
Lassa fever virus is one of the most dangerous viruses of arenaviridae family, causing more than 500,000 infections per year in Africa. The fatality rate for hospitalized patients is as high as 20%.
Qi, Xiaoxuan
core  

Non-neutralizing antibodies elicited by recombinant Lassa-Rabies vaccine are critical for protection against Lassa fever [PDF]

, 2018
Lassa fever (LF), caused by Lassa virus (LASV), is a viral hemorrhagic fever for which no approved vaccine or potent antiviral treatment is available. LF is a WHO priority disease and, together with rabies, a major health burden in West Africa.
Hagen, Katie R., Cooper, Kurt, Wirblich, Christoph, Schnell, Matthias J., Jahrling, Peter B., Tan, Gene, Schnell, Matthias J, Abreu-Mota, Tiago, Johnson, Reed F.   +8 more
core   +1 more source

Lassa Fever: Another Infectious Menace

, 2009
Nigeria is presently suffering from another Lassa fever epidemic. This was confirmed in the statement of the Minister of Health of the Federation in which he said, “There has been an upsurge in the reported cases of Lassa fever since the beginning of ...
A Fowotade, Fowotade, A, Adewuyi, GM, BT Adewuyi, Adewuyi, BT, GM Adewuyi   +5 more
core   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, Volume 13, Issue 12, 27 February 2026.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Lassa Fever: From a Nigerian Town to a Global Threat

, 2023
Lassa fever is associated with high morbidity and mortality rate. This is due to the primary host of Lassa virus being a rodent of the genus Mastomy’s, also referred to as ‘multimammate rat’.
Almasaoudy, Ranya, Rounds, Juliana A, Lopez, Joshelin G, Avlarado, margarita   +3 more
core  

Mass media reportage of Lassa fever in Nigeria: a viewpoint

Journal of International Medical Research, 2020
In Nigeria, the mass media are used independently or complementarily in health promotion activities to achieve positive lifestyle changes. The mass media can play a positive role in combating the Lassa fever epidemic and its attendant fatality in Nigeria.
Joseph Oluchukwu Wogu, Christiana Ogeri Chukwu, Kenneth Adibe Nwafor, Ekenechukwu Anazor Anikpe, Joel Chinedum Ugwuoke, Chinyere Christiana Ugwulor-Onyinyechi, Chiedu Eseadi   +6 more
doaj   +1 more source

C-Reactive Protein and Association with Disease Severity in Hospitalized Adult Lassa Fever Patients in Nigeria

Background : Lassa fever poses a significant health burden in west Africa. The pathophysiology of Lassa fever and determinants of clinical spectrum of disease remain poorly understood.
Okogbenin, Sylvanus, Tembo, John, Honeyborne, Isobella, Erameh, Cyril, Zumla, Adam, Haider, Najmul, Asogun, Danny, Ogbainin, Ephraim, Omono, Adoghe Patricia, Elton, Linzy, Zumla, Alimuddin, Ntoumi, Francine, Okojie, Festus Oloruntoba, Eifediyi, Reuben, Ahmed, Rizwan, Dic-Ijiewere, Ebenezer Oseremen, Christopher, Okpunu Eseoleleti, Huemomen, Faith Unuabonah, Okoeguale, Joseph, McHugh, Timothy D   +19 more
core   +1 more source

Improving the care of Lassa fever patients: re-evaluating the use of Ribavirin and characterising cardiovascular function

Lassa fever is a viral haemorrhagic fever, endemic to several West African countries. Case fatality rates average 30% across the literature. Ribavirin, a broad-spectrum antiviral agent, has been used to treat Lassa fever for four decades.
Salam, Alex
core   +1 more source

Number of Lassa fever clinical studies published per year.

, 2021
Number of Lassa fever clinical studies published per year.
Laura Merson (363604), Astrid Erber (11462782), Antoine Flahault (28740), Josephine Bourner (11462776), Piero L. Olliaro (9010184), Alex Paddy Salam (11098949), Sulaiman Jalloh (11462779)   +6 more
core   +1 more source