Results 61 to 70 of about 14,864 (203)

High fatality of Lassa fever outbreak in Kenema District- Sierra Leone, January 2023

Journal of Interventional Epidemiology and Public Health
Introduction: In Sierra Leone, Lassa fever is an endemic disease with an estimated 16% fatality rate among hospitalized cases. On January 16, 2023, the Kenema District Health Management Team received notification about suspected cases of Lassa fever from
Binta Bah, Umaru Nyallay, Philp Gevao, Joel Mansaray, Paul Mansary, Umaru Sesay, Anna Jammeh, Solomon Aiah Sogbeh, Amara Alhaji Sheriff, Joseph Sam Kanu, James Sylvester Squire, Adel Hussein Elduma, Mohamed Alex Vandi, Gebrekrstos Negash Gebru   +13 more
doaj   +1 more source

Arbovirus infections and viral haemorrhagic fevers in Uganda : a serological survey in Karamoja district, 1984 [PDF]

, 1989
Présentation des résultats de l'enquête effectuée sur 132 habitants du district de Karamoja en Ouganda, qui ont été examinés pour la recherche d'anticorps contre certains arbovirus dont la fièvre ...
Gonzalez, Jean-Paul, Hannoun, C., Helynck, B., Larouze, B., Mercier, E., Rodhain, F.   +5 more
core   +1 more source

Retrospective Study on Liberation in Dogs Undergoing Mechanical Ventilation for Longer Than 24 Hours

Journal of Veterinary Emergency and Critical Care, Volume 36, Issue 2, Page 235-247, March/April 2026.
ABSTRACT Objective To describe liberation in a population of dogs undergoing ≥24 h of mechanical ventilation (MV) and to assess for differences between successful and unsuccessful liberation attempts as well as adherence to criteria for veterinary and human readiness to discontinue MV. Design Retrospective study.
Abigail E. McNally, Thomas D. Greensmith, Stefano Cortellini   +2 more
wiley   +1 more source

An outbreak investigation of a highly fatal Lassa Fever in Bo District, Sierra Leone, 2023

Journal of Interventional Epidemiology and Public Health
Introduction: Lassa fever is endemic in West Africa, with an estimated 100,000 to 300,000 infections and 5,000 deaths annually. On February 1, 2023, the Bo District Surveillance Team received a notification from a community in the district about ...
Ibrahim Conteh, Hassan Swarray, Gbessay Saffa, Amara Alhaji Sheriff, Solomon Aiah Sogbeh, Umaru Sesay, Kassim Kamara, Anna Jammeh, Adel Hussein Elduma, Gebrekrstos Negash Gebru   +9 more
doaj   +1 more source

Some Remarks about the Complexity of Epidemics Management

, 2017
Recent outbreaks of Ebola, H1N1 and other infectious diseases have shown that the assumptions underlying the established theory of epidemics management are too idealistic. For an improvement of procedures and organizations involved in fighting epidemics,
Brown, André EX, Ch'ng, Quee-Lim, Currie, Michael, Grundy, Laura J, Hokanson, Jim, Javer, Avelino, Kerr, Rex, Lee, Chee Wai, Li, Chris, Li, Kezhi, Schafer, William R, Yemini, Eviatar   +11 more
core   +4 more sources

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, Volume 13, Issue 12, 27 February 2026.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Pathogenesis of Lassa Fever

Viruses, 2012
Lassa virus, an Old World arenavirus (family Arenaviridae), is the etiological agent of Lassa fever, a severe human disease that is reported in more than 100,000 patients annually in the endemic regions of West Africa with mortality rates for ...
David H. Walker, Nadezhda E. Yun
doaj   +1 more source

Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage [PDF]

, 2010
Background Several arenaviruses cause severe hemorrhagic fever and aseptic meningitis in humans for which no licensed vaccines are available. A major obstacle for vaccine development is pathogen heterogeneity within the Arenaviridae family.
Maya F Kotturi, Jason Botten, Matt Maybeno, John Sidney, Jean Glenn, Huynh-Hoa Bui, Carla Oseroff, Shane Crotty, Bjoern Peters, Howard Grey, Daniel M Altmann, Michael J Buchmeier, Alessandro Sette   +12 more
core   +2 more sources

A cluster of nosocomial Lassa fever cases in a tertiary health facility in Nigeria: Description and lessons learned, 2018

International Journal of Infectious Diseases, 2019
Background: Lassa fever is an acute viral haemorrhagic disease endemic in Nigeria. The 2018 Lassa fever outbreak in Nigeria was unprecedented, with 8% of all cases occurring among healthcare workers (HCWs).
Chioma C. Dan-Nwafor, Oladipupo Ipadeola, Elizabeth Smout, Elsie Ilori, Ayodele Adeyemo, Chukwuma Umeokonkwo, Damian Nwidi, Williams Nwachukwu, Winifred Ukponu, Emeka Omabe, Uchenna Anaebonam, Nneka Igwenyi, Gordon Igbodo, Womi Eteng, Ikemefule Uzoma, Muhammed Saleh, Joseph Agboeze, Samuel Mutbam, Tanyth de Gooyer, Rosie Short, Everistus Aniaku, Robinson Onoh, Emeka Ogah, Patrick Nguku, John Oladejo, Clement Peter, Olubunmi Ojo, Chikwe Ihekweazu   +27 more
doaj   +1 more source

Methods of Engaging Interest‐Holders in Healthcare Evidence Syntheses: A Scoping Review

Cochrane Evidence Synthesis and Methods, Volume 4, Issue 1, January 2026.
ABSTRACT Introduction Engaging interest‐holders in health care evidence syntheses may make evidence syntheses more relevant, useful, and accessible. However, the best way(s) to engage interest‐holders within the evidence synthesis process remain unknown.
Alex Todhunter‐Brown, Jennifer Petkovic, Christine Chang, Ursula Griebler, Ailish Hannigan, Jennifer Hilgart, Basharat Hussain, Janet Jull, Christina Koscher‐Kien, Dominic Ledinger, Barbara Nussbaumer‐Streit, Oyekola Oloyede, Eve Tomlinson, Shoba Dawson, Omar Dewidar, Sean Grant, Lyubov Lytvyn, Thomas W. Concannon, Leonila Dans, Denny John, Zoe Jordan, Evan Mayo‐Wilson, Chris McCutcheon, Francesco Nonino, Danielle Pollock, Karine Toupin April, Pauline Campbell, Joanne Khabsa, Olivia Magwood, Vivian Welch, Peter Tugwell   +30 more
wiley   +1 more source