Results 61 to 70 of about 237,919 (194)

High fatality of Lassa fever outbreak in Kenema District- Sierra Leone, January 2023

Journal of Interventional Epidemiology and Public Health
Introduction: In Sierra Leone, Lassa fever is an endemic disease with an estimated 16% fatality rate among hospitalized cases. On January 16, 2023, the Kenema District Health Management Team received notification about suspected cases of Lassa fever from
Binta Bah, Umaru Nyallay, Philp Gevao, Joel Mansaray, Paul Mansary, Umaru Sesay, Anna Jammeh, Solomon Aiah Sogbeh, Amara Alhaji Sheriff, Joseph Sam Kanu, James Sylvester Squire, Adel Hussein Elduma, Mohamed Alex Vandi, Gebrekrstos Negash Gebru   +13 more
doaj   +1 more source

Assessment of Knowledge and Sources of Information on Lassa Fever Infection Among the Undergraduate Students of Ebonyi State University, Nigeria

SAGE Open, 2021
Lassa fever is a zoonotic disease characterized by acute viral hemorrhagic fever, endemic in West Africa including Nigeria. The study assessed the knowledge and sources of information on Lassa fever infection among the undergraduate students of Ebonyi ...
MaryJoy Umoke, Prince Christian Ifeanachor Umoke, Chioma Adaora Nwalieji, Rosemary N. Onwe, Ifeanyi Emmanuel Nwafor, Samson Olaoluwa Agbaje, Ignatius O. Nwimo   +6 more
doaj   +1 more source

Widespread SARS‐CoV‐2 Transmission Despite Limited Reported Cases and Clinical Disease: Exploring the Role of Pre‐Existing Humoral Immunity to SARS‐CoV‐2 in Eastern Sierra Leone

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Background Since December 2019, SARS‐CoV‐2 has infected over 700 million people and caused > 7 million deaths. While much of the global north was severely affected, sub‐Saharan Africa was relatively spared. Possible reasons include a younger population, fewer comorbidities, and pre‐existing immunity.
Robert J. Samuels, Nell G. Bond, Ibrahim Sumah, Donald S. Grant, Mohamed S. Kamara, Lydia Bazzano, Camilo Fernandez, Rodrigo Borrega, Sruti Chandra, Celia R. Glezer, John S. Schieffelin, Troy D. Moon   +11 more
wiley   +1 more source

An outbreak investigation of a highly fatal Lassa Fever in Bo District, Sierra Leone, 2023

Journal of Interventional Epidemiology and Public Health
Introduction: Lassa fever is endemic in West Africa, with an estimated 100,000 to 300,000 infections and 5,000 deaths annually. On February 1, 2023, the Bo District Surveillance Team received a notification from a community in the district about ...
Ibrahim Conteh, Hassan Swarray, Gbessay Saffa, Amara Alhaji Sheriff, Solomon Aiah Sogbeh, Umaru Sesay, Kassim Kamara, Anna Jammeh, Adel Hussein Elduma, Gebrekrstos Negash Gebru   +9 more
doaj   +1 more source

Effectiveness of Yoruba language radio jingles in promoting knowledge, attitude and practices regarding Lassa fever among women in Ondo state, Nigeria

Journal of Public Health in Africa, 2020
Background: Lassa fever is one of the known Neglected Tropical Diseases (NTDs) that plague some states in Nigeria. Radio jingles in indigenous language have been adopted as a veritable risk communication approach to promote public knowledge in the bid to
Charity Ben-Enukora, Olushola Oyero, Nelson Okorie, Kehinde Oyesomi, Babatunde Adeyeye   +4 more
doaj   +1 more source

AP‐1‐Targeting Decoy Oligonucleotides: Mechanisms and Therapeutic Potential as Modulators of Inflammatory Pathways

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Numerous cellular functions, such as apoptosis, proliferation, differentiation, survival, transformation and cell migration, are regulated by a crucial transcription factor called activator protein 1 (AP‐1). Growing evidence indicates that AP‐1 is involved in severe conditions like fibrosis, cancer, and organ damage, as well as inflammatory ...
Maryam Mahjoubin‐Tehran, Samaneh Rezaei, Vasily N. Sukhorukov, Amin Jalili, Prashant Kesharwani, Amirhossein Sahebkar   +5 more
wiley   +1 more source

Use of Favipiravir to Treat Lassa Virus Infection in Macaques

Emerging Infectious Diseases, 2018
Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection.
Kyle Rosenke, Heinz Feldmann, Jonna B. Westover, Patrick William Hanley, Cynthia Martellaro, Friederike Feldmann, Greg Saturday, Jamie Lovaglio, Dana P. Scott, Yousuke Furuta, Takashi Komeno, Brian B. Gowen, David Safronetz   +12 more
doaj   +1 more source

Canine chronic idiopathic rhinitis: management and outcome – a single‐centre retrospective observational study

Journal of Small Animal Practice, Volume 67, Issue 5, Page 460-470, May 2026.
Objectives Canine chronic idiopathic rhinitis is a common cause of nasal disease in dogs but data reporting outcomes following treatment is lacking. The aim was to describe pre‐ and post‐referral management and outcomes of dogs diagnosed with canine chronic idiopathic rhinitis at a single referral centre.
P. M. N. Henry, R. Rizzo, Y. Tan, A. M. Boag, J. Del‐Pozo, G. A. Woods   +5 more
wiley   +1 more source

Evolution of Point‐of‐Care Nucleic Acid Testing: From Amplification Chemistry to Intelligent and Data‐Driven Systems for Public Health

Aggregate, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in integrated point‐of‐care testing (POCT) systems for public health, encompassing isothermal nucleic acid amplification, CRISPR‐based signal amplification, device integration, and chemometric/artificial intelligence‐assisted data interpretation, with applications in infectious disease surveillance, food and ...
Yan Du, Jiaqi Li, Jinghong Li
wiley   +1 more source

Lassa Fever: From a Nigerian Town to a Global Threat [PDF]

, 2023
Lassa fever is associated with high morbidity and mortality rate. This is due to the primary host of Lassa virus being a rodent of the genus Mastomy’s, also referred to as ‘multimammate rat’.
Almasaoudy, Ranya, Rounds, Juliana A, Lopez, Joshelin G, Avlarado, margarita   +3 more
core