Increase in atmospheric carbonyl sulphide since the last glacial period
, 2023 Abstract Carbonyl sulphide (COS) is the most abundant atmospheric sulphur gas with links to terrestrial and oceanic productivity1. A 52,000-year COS record was recovered from a South Pole ice core. We find evidence for COS production in the ice sheet that alters the atmospheric signal in the ice but can be corrected for using sea salt sodium as
openaire +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Impact of millennial-scale oceanic variability on the Greenland ice-sheet evolution throughout the last glacial period [PDF]
Climate of the Past, 2019 Temperature reconstructions from Greenland ice-sheet (GrIS) ice cores indicate the occurrence of more than 20 abrupt warmings during the last glacial period (LGP) known as Dansgaard-Oeschger (D-O) events.
I. Tabone +8 more
doaj +1 more source
Steppes, savannahs, forests and phytodiversity reservoirs during the Pleistocene in the Iberian Peninsula [PDF]
, 2010 A palaeobotanical analysis of the Pleistocene floras and vegetation in the Iberian Peninsula shows the existence of patched landscapes with Pinus woodlands, deciduous and mixed forests, parklands (savannah-like), shrublands, steppes and grasslands ...
Agustí +259 more
core +3 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Geochronological reconstruction of the glacial evolution in the Ésera valley (Central Pyrenees) during the Late Pleistocene and Holocene [PDF]
Climate of the PastSince the MIS (Marine Isotope Stage) 4, glaciers in the Pyrenees were subject to intricate dynamics, encompassing some advances and retreats not always aligned with the fluctuations observed in other European glaciers.
I. Vidaller +3 more
doaj +1 more source
Ice Core Records of Antarctic Warming Events in the Last Glacial Period [PDF]
, 2016 第3回極域科学シンポジウム 横断セッション「海・陸・氷床から探る後期新生代の南極寒冷圏環境変動」11月26日（月） 国立国語研究所 ...
Hideaki Motoyama +8 more
core +1 more source
Sea surface temperature changes in the southern California borderlands during the last glacial-interglacial cycle [PDF]
, 1996 A variety of evidence suggests that average sea surface temperatures (SSTs) during the last glacial maximum in the California Borderlands region were significantly colder than during the Holocene.
Bandy +52 more
core +2 more sources
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Climate deteriorations and Neanderthal demise in interior Iberia
Scientific Reports, 2018 Time and circumstances for the disappearance of Neanderthals and its relationship with the advent of Modern Humans are not yet sufficiently resolved, especially in case of the Iberian Peninsula.
D. Wolf +12 more
doaj +1 more source