Results 81 to 90 of about 160,127 (291)

Spatio-temporal dynamics of speleothem growth and glaciation in the British Isles [PDF]

open access: yesClimate of the Past
Reconstructing the spatio-temporal dynamics of glaciations and permafrost largely relies on surface deposits and is therefore a challenge for every glacial period older than the last due to erosion.
S. Panitz   +13 more
doaj   +1 more source

Ventilation history of Nordic Seas overflows during the last (de)glacial period revealed by species-specific benthic foraminiferal 14C dates [PDF]

open access: yes, 2017
Formation of deep water in the high-latitude North Atlantic is important for the global meridional ocean circulation, and its variability in the past may have played an important role in regional and global climate change. Here we study ocean circulation
Ezat, MM   +6 more
core   +1 more source

Improving chronological control for environmental sequences from the last glacial period [PDF]

open access: yesQuaternary Geochronology, 2018
Recognition of palaeoclimatic instability in the Greenland ice cores has spurred researchers to identify corresponding evidence in other terrestrial records from the last glacial stage. Such evidence is critical for establishing how much environmental stress precipitated Neanderthal and Late Pleistocene megafaunal extinctions, although a need for ...
Rebecca M. Briant   +7 more
openaire   +5 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

The De Long Trough: a newly discovered glacial trough on the East Siberian continental margin [PDF]

open access: yesClimate of the Past, 2017
Ice sheets extending over parts of the East Siberian continental shelf have been proposed for the last glacial period and during the larger Pleistocene glaciations.
M. O'Regan   +23 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Identification of Potential Paleoislands in the Mediterranean Sea During the Last Glacial Cycle

open access: yesEuropean Journal of Geography
The Last Glacial Period (LGP) significantly altered sea levels and landscapes across the globe, with the Mediterranean Sea being no exception. During this period, fluctuating sea levels exposed numerous landmasses, some of which may have served as ...
Pablo Fraile Jurado   +1 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Ice age unfrozen: severe effect of the last interglacial, not glacial, climate change on East Asian avifauna

open access: yesBMC Evolutionary Biology, 2017
Background The glacial-interglacial cycles in the Pleistocene caused repeated range expansion and contraction of species in several regions in the world.
Feng Dong   +8 more
doaj   +1 more source

South Asian monsoon history over the past 60 kyr recorded by radiogenic isotopes and clay mineral assemblages in the Andaman Sea [PDF]

open access: yes, 2015
The Late Quaternary variability of the South Asian (or Indian) monsoon has been linked with glacial‐interglacial and millennial scale climatic changes but past rainfall intensity in the river catchments draining into the Andaman Sea remains poorly ...
Ali, Sajid   +8 more
core   +1 more source

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