Results 91 to 100 of about 14,197,112 (305)
Acta OncologicaBackground and purpose: Colorectal cancer (CRC) can affect return to work and sustained work participation. While employment rates have been studied, less is known about how survivors manage work demands after returning, despite frequent long-term ...
Pernille Pedersen +10 more
doaj +1 more source
Impairments that Influence Physical Function among Survivors of Childhood Cancer
Children, 2015 Children treated for cancer are at increased risk of developing chronic health conditions, some of which may manifest during or soon after treatment while others emerge many years after therapy.
Carmen L. Wilson +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Preserving Fertility in Children and Adolescents with Cancer
Children, 2014 In the face of excellent survival rates for pediatric and adolescent cancer, preserving the opportunity to have biological children is an important component of long term quality of life. Yet, modern chemotherapeutic regimens continue to pose a threat to
Jennifer M. Levine
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Previous Treatments for Schizophrenia: Efficacy and Adverse Effects.
, 2005 This chapter presents the history of treatment of schizophrenia from 1890 to 1990. Understanding these older treatments is important for the study of older patients with schizophrenia, because the persistence of many of the adverse effects of these ...
Harvey, Philip D, Philip D. Harvey
core +1 more source
Acta OncologicaBackground and purpose: Loss of skeletal muscle mass (SMM) is common during systemic cancer treatment, but the magnitude and variability across cancer and treatment types remain uncertain.
Lukas Svendsen +11 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The late effects of cancer and cancer treatment:a rapid review
, 2014 This paper aims to synthesize literature about the definition, prevalence, onset and treatments associated with late effects. A rapid review was conducted using Google Scholar to identify reviews related to the late effects of adult-onset cancers. Papers
Donnelly, Michael; id_orcid +1 more
core +2 more sources