Results 101 to 110 of about 14,197,112 (305)

Long-term cardiac effects of modern treatment for Hodgkin’s lymphoma

open access: yesCardio-Oncology
Background Hodgkin’s lymphoma (HL) is a hematological malignancy that affects both children and young adults. Traditional treatment is associated with a life-time prevalence of cardiac disease exceeding 50%.
Anders W Bjerring   +8 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Late effects of cancer in general practice

open access: yes
Late effects after cancer treatment are common, and more follow-up care will occur in general practice. This review shows how a systematic, proactive approach can ensure appropriate care for all patients and identify those needing extra support.
Jarbøl, Dorte Ejg; id_orcid   +2 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

V Congress of Polish Society of Neuroendocrinology 21–22 September, 2018 Kraków — Late abstracts

open access: yes, 2018
V Congress of Polish Society of Neuroendocrinology 21–22 September, 2018 Kraków — Late ...
Abstracts, Late
core  

Late-Stage Diversification of Natural Products

open access: yes, 2020
Late-stage diversification of natural products is an efficient way to generate natural product derivatives for drug discovery and chemical biology. Benefiting from the development of site-selective synthetic methodologies, late-stage diversification of ...
Benke Hong (1525480)   +2 more
core   +1 more source

Neurolinguistic late-side effects of childhood cancer treatment [PDF]

open access: yes, 2016
The survival rate for children with brain cancer and tumours (CNS) has been going up in the last years. At the same time, different communicative, cognitive and psychological late-effects have been observed.
Álvarez Benito, Gloria   +1 more
core   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

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