Results 91 to 100 of about 180,240 (308)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Steppes, savannahs, forests and phytodiversity reservoirs during the Pleistocene in the Iberian Peninsula [PDF]

open access: yes, 2010
A palaeobotanical analysis of the Pleistocene floras and vegetation in the Iberian Peninsula shows the existence of patched landscapes with Pinus woodlands, deciduous and mixed forests, parklands (savannah-like), shrublands, steppes and grasslands ...
Agustí   +259 more
core   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Development of the late glacial Baltic basin and the succession of vegetation cover as revealed at Palaeolake Haljala, northern Estonia [PDF]

open access: yesEstonian Journal of Earth Sciences, 2009
The 4.5 m thick Haljala sequence in North Estonia was studied to provide information on palaeoenvironmental changes between 13 800 and 11 300 cal yr BP.
Saarse, Leili   +5 more
doaj  

Impact of late glacial climate variations on stratification and trophic state of the meromictic lake Längsee (Austria): validation of a conceptual model by multi proxy studies

open access: yesJournal of Limnology, 2002
Selected pigments, diatoms and diatom-inferred phosphorus (Di-TP) concentrations of a late glacial sediment core section of the meromictic Längsee, Austria, were compared with tephra- and varve-dated pollen stratigraphic and geochemical results.
Jens MÜLLER   +4 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Last Glacial Maximum cooling induced positive moisture balance and maintained stable human populations in Australia

open access: yesCommunications Earth & Environment
Long-standing interpretations of the Last Glacial Maximum (21,000 ± 2000 years ago) in Australia suggest that the period was extremely cold and arid, during which the Indo-Australian summer monsoon system collapsed, and human populations declined and ...
Haidee Cadd   +7 more
doaj   +1 more source

Significance of Hippophae rhamnoides L. in evolution of the Eemian Interglacial' flora in Warsaw area

open access: yesActa Societatis Botanicorum Poloniae, 2014
Palynologic studies of sediments from Warsaw-Wawrzyszew and other sites in the Warsaw Basin enabled to analyze main occurrence phases of Hippophae rhamnoides during the widely understood Lake Pleistocene interglacial warming.
Krzysztof M. Krupiński
doaj   +1 more source

Organic carbon isotope record since the Late Glacial period from peat in the North Bank of the Yangtze River, China

open access: yesEuropean Journal of Remote Sensing, 2020
Detailed organic carbon isotope (δ13Corg) measurements were conducted on two peat sequences recovered from the north bank of the Yangtze River, East China. Seven radiocarbon dates provided firm age control of this δ13Corg record and reveal palaeoclimatic
Hui Zhou   +6 more
doaj   +1 more source

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