Results 81 to 90 of about 178,686 (262)

Steppes, savannahs, forests and phytodiversity reservoirs during the Pleistocene in the Iberian Peninsula [PDF]

open access: yes, 2010
A palaeobotanical analysis of the Pleistocene floras and vegetation in the Iberian Peninsula shows the existence of patched landscapes with Pinus woodlands, deciduous and mixed forests, parklands (savannah-like), shrublands, steppes and grasslands ...
Agustí   +259 more
core   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Palaeoenvironmental record of the last 70 000 yr in San Felipe Basin, Sonora desert, Mexico: preliminary results [PDF]

open access: yesGeofísica Internacional, 1999
Preliminary results of a palaeoenvironmental research which includes particle size analyses, diatom and rock-magnetic analyses for a 9.5 m long core from Laguna Seca de San Felipe (LSSF), Baja California, are presented.
De la O Villanueva, Margarita   +3 more
doaj  

Northeastern Atlantic benthic foraminifera during the last 45,000 years: Changes in productivity seen from the bottom up [PDF]

open access: yes, 1995
We studied benthic foraminifera from the last 45 kyr in the >63 mu m size fraction in Biogeochemical Ocean Flux Studies (BOFS) cores 5K (50 degrees 41.3'N, 21 degrees 51.9'W, depth 3547 m) and 14K (58 degrees 37.2'N, 19 degrees 26.2'W, depth 1756 m), at ...
Booth, L   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

A new Late-glacial and Holocene record of vegetation and fire history from Lago del Greppo, northern Apennines, Italy [PDF]

open access: yes, 2018
Detailed Late-glacial and Holocene palaeoenvironmental records from the northern Apennines with a robust chronology are still rare, though the region has been regarded as a main area of potential refugia of important trees such as Picea abies and Abies ...
Ammann, Brigitta   +3 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Impact of late glacial climate variations on stratification and trophic state of the meromictic lake Längsee (Austria): validation of a conceptual model by multi proxy studies

open access: yesJournal of Limnology, 2002
Selected pigments, diatoms and diatom-inferred phosphorus (Di-TP) concentrations of a late glacial sediment core section of the meromictic Längsee, Austria, were compared with tephra- and varve-dated pollen stratigraphic and geochemical results.
Jens MÜLLER   +4 more
doaj   +1 more source

Organic carbon isotope record since the Late Glacial period from peat in the North Bank of the Yangtze River, China

open access: yesEuropean Journal of Remote Sensing, 2020
Detailed organic carbon isotope (δ13Corg) measurements were conducted on two peat sequences recovered from the north bank of the Yangtze River, East China. Seven radiocarbon dates provided firm age control of this δ13Corg record and reveal palaeoclimatic
Hui Zhou   +6 more
doaj   +1 more source

Geology of Tindfjallajökull volcano, Iceland [PDF]

open access: yes, 2018
The geology of Tindfjallajökull volcano, southern Iceland, is presented as a 1:50,000 scale map. Field mapping was carried out with a focus on indicators of past environments.
Dave McGarvie   +10 more
core   +3 more sources

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