Results 101 to 110 of about 1,913,951 (381)

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Die spätmittelalterlichen Steigbügeltypen aus dem Gebiet Polens

open access: yesFasciculi Archaeologiae Historicae, 1992
...
Witold Świętosławski
doaj  

Early Indicators of Later Work Levels, Disease, and Death [PDF]

open access: yes
This paper summarizes a collaborative project designed to create a public-use tape suitable for a prospective study of aging among a random sample of 39,616 men mustered into 331 companies of the Union Army.
Larry T. Wimmer, Robert W. Fogel
core  

Gent en zijn advocaten: een historische wandeling door de stad [PDF]

open access: yes, 2012
This illustrated booklet tells the story off the presence of lawyers in Ghent, heart of the old county of Flanders. Commenting on places of memory (the Count's castle, the Town Hall, the Law Faculty, the Palace of Justice...), it deals with the history ...
Martyn, Georges
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Of Boyling and Seething: A Re-evaluation of the Common Cooking Terms in Connection with Brewing

open access: yesEXARC Journal, 2018
Modern chemistry provides us with a deeper understanding of fermentation, but that does not necessarily translate into an easier interpretation of medieval recipes.
Susan Verberg
doaj  

The Later Middle Ages [PDF]

open access: bronze, 1961
Coburn V. Graves
openalex   +1 more source

Some aspects of the ceramics techonology in the late middle ages in Belarus [PDF]

open access: yes, 2016
Adding national flavor to agricultural tourist houses is connected with the question of traditional ceramics for national cuisine, which forms an important element of the local colour of the interiors.
Zdanovich, N. I.
core  

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

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