Results 181 to 190 of about 2,125,321 (405)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Dietary inequality marker reveals 10,000 years of gender and cultural disparity in Europe. [PDF]

PNAS Nexus
Colleter R, Jaouen K, Garcia D, Richards MP.   +3 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Ideas of Power in the Late Middle Ages, 1296-1417

, 2011
J. Canning
semanticscholar   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Obligate faunivorous megatheropod size class patterns across the Jurassic-Cretaceous Periods. [PDF]

PeerJ
Boisvert C, Perkins J, Morrison C, Gascoigne SJL, Holtz TR, Curtice B.   +5 more
europepmc   +1 more source

The Effects of Intensive Nutrition Education on Late Middle-Aged Adults with Type 2 Diabetes- Randomized Trial

Imadabathini Sumana, Devaki Talluri, P. Madhurya Rupa, G. Swetha Sree   +3 more
openalex   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Neurobiology of language in autism: a systematic review of pediatric studies. [PDF]

Brain Imaging Behav
Witt KM, Carnett A.
europepmc   +1 more source

The Representation of Angels and Angelic Orders from the Late Middle Ages Through the Reformation c.1450 -c.1650

, 2010
Mary Agnes Murphy
openalex   +1 more source