Results 191 to 200 of about 2,125,321 (405)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

La vaisselle en terre cuite utilisée au xive s. à l’hôpital Saint-Julien de Chartres (Eure-et-Loir)

open access: yesRevue Archéologique du Centre de la France
Grasping 14th century Chartres pottery was made possible thanks to the excavations of a latrine collection pit at Saint-Julien hospital, an institution for the blind founded in 1291 on a plot of land on the outer periphery of the town, in Faubourg Saint ...
Magali Gary
doaj  

Specialised and persistent raw material procurement by humans in the Middle Pleistocene. [PDF]

open access: yesNat Commun
Will M   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy