Results 71 to 80 of about 1,224,700 (310)

Profile of Women with Late Menstrual Period

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2013
Objective: To know the profile of women with late menstrual period in Raden Saleh Clinic Jakarta in 2008 - 2011. Method: This was a descriptive study with 400 samples from medical records, choosen by random sampling.
Eka R. Gunardi
doaj   +1 more source

Regional spore dispersal as a factor in disease risk warnings for potato late blight: a proof of concept

open access: yes, 2009
This study develops and tests novel approaches that significantly reduce the fungicide input necessary for potato late blight control while maintaining the required high level of disease control.
Skelsey, P.   +5 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

STATE INTERVENTIONISM IN THE LATE CLASSIC MAYA PALENQUE POLITY: HOUSEHOLD AND COMMUNITY ARCHAEOLOGY AT EL LACANDON [PDF]

open access: yes, 2013
Archaeological materials from seven excavated households (three commoner, three elite and a super-elite) from El Lacandón, a rural settlement of the Ancient Maya Palenque polity in Chiapas, Mexico; are analyzed to examine how households and communities ...
LOPEZ BRAVO, ROBERTO
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Late modern English: novel encounters/ edited by Merja Kytö, Erik Smitterberg.

open access: yes, 2020
Includes bibliographical references and index."The past few decades have witnessed an unprecedented surge of interest in the language of the Late Modern English period.
Kytö Merja, Smitterberg Erik
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Home - About - Disclaimer - Privacy