Results 71 to 80 of about 391,534 (273)

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Impact of childhood maltreatment on adolescents’ mental health– a longitudinal study based on dual-factor model

BMC Psychology
The dual-factor model (DFM) of mental health has received increasing support in recent years. However, researchers have limited knowledge regarding the longitudinal changes in the DFM of mental health.
Qingji Zhang, Yeman Tu, Shunyu Yao, Qingdi Zhang, Jiangnan Liu, Peng Quan   +5 more
doaj   +1 more source

Patterns of Substance Use Across the First Year of College and Associated Risk Factors

Frontiers in Psychiatry, 2015
Starting college is a major life transition. This study aims to characterize patterns of substance use across a variety of substances across the first year of college and identify associated factors.
Seung Bin eCho, Seung Bin eCho, Danielle C. Llaneza, Danielle C. Llaneza, Amy E. Adkins, Amy E. Adkins, Megan eCooke, Kenneth S. Kendler, Shaunna L. Clark, Danielle M. Dick, Danielle M. Dick, Danielle M. Dick   +11 more
doaj   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Longitudinal Model Building Using Latent Transition Analysis: An Example Using School Bullying Data

Frontiers in Psychology, 2018
Applications of latent transition analysis (LTA) have emerged since the early 1990s, with numerous scientific findings being published in many areas, including social and behavioral sciences, education, and public health.
Ji Hoon Ryoo, Cixin Wang, Susan M. Swearer, Michael Hull, Dingjing Shi   +4 more
doaj   +1 more source

Predictors and Changes in Paternal Perinatal Depression Profiles—Insights From the DREAM Study

Frontiers in Psychiatry, 2020
In contrast to the large body of research on maternal perinatal depression, paternal perinatal mental health has received little attention; and longitudinal studies on paternal perinatal depression, following (expectant) fathers over time, are ...
Susan Garthus-Niegel, Susan Garthus-Niegel, Susan Garthus-Niegel, Andreas Staudt, Patricia Kinser, Silje Marie Haga, Filip Drozd, Sophie Baumann   +7 more
doaj   +1 more source

First-order transitions in glasses and melts induced by solid superclusters nucleated and melted by homogeneous nucleation instead of surface melting

, 2019
Supercooled liquids give rise, by homogeneous nucleation, to solid superclusters acting as building blocks of glass, ultrastable glass, and glacial glass phases before being crystallized.
Tournier, Robert F.
core   +3 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

A latent transition analysis of bullying and victimization in Chinese primary school students.

PLoS ONE, 2017
Bullying is a social phenomenon that impacts a large number of children and young people, worldwide. This study aimed to longitudinally examine the development of bullying and victimization in Chinese students in grades 4, 5, and 6.
Yiqin Pan, Hongyun Liu, Puiyi Lau, Fang Luo   +3 more
doaj   +1 more source

Determinants of cross-border bank acquisitions in transition economies: a latent class analysis [PDF]

, 2008
We analyze the microeconomic determinants of cross-border bank acquisitions in 16 transition economies over the period 1996-2006. By using a latent class discrete choice model we explicitly incorporate the macroeconomic and institutional heterogeneity of
de Haan, Jakob, Poghosyan, Tigran
core