Results 51 to 60 of about 391,534 (273)

Contraceptive Behavior Dynamics and Unintended Pregnancy: A Latent Transition Analysis

open access: yesDemography, 2023
Abstract The average U.S. woman wants to have two children; to do so, she will spend about three years pregnant, postpartum, or trying to become pregnant, and three decades trying to avoid pregnancy. However, few studies have examined individual patterns of contraceptive use over time. These trajectories are important to understand given
Alison Swiatlo   +5 more
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Latent Markov model for longitudinal binary data: An application to the performance evaluation of nursing homes

open access: yes, 2009
Performance evaluation of nursing homes is usually accomplished by the repeated administration of questionnaires aimed at measuring the health status of the patients during their period of residence in the nursing home.
Bartolucci, Francesco   +2 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Social Integration in Higher Education and Development of Intrinsic Motivation: A Latent Transition Analysis

open access: yesFrontiers in Psychology, 2022
This study, based on the self-determination theory, investigates the link between university students' social peer and teacher integration and intrinsic motivation development.
Marion Reindl   +2 more
doaj   +1 more source

Alpha helix-coil phase transition: analysis of ab initio theory predictions

open access: yes, 2007
In the present paper we present results of calculations obtained with the use of the theoretical method described in our preceding paper [1] and perform detail analysis of alpha helix-random coil transition in alanine polypeptides of different length. We
102   +48 more
core   +1 more source

A complex network perspective on clinical science [PDF]

open access: yes, 2016
Contemporary classification systems for mental disorders assume that abnormal behaviors are expressions of latent disease entities. An alternative to the latent disease model is the complex network approach.
Curtiss, Joshua   +2 more
core   +2 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Social and therapeutic decline earlier than physical and psychological domains after discharge in heart failure patients: A patient-reported outcome measurements of latent transition analysis

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundAmong patients with chronic heart failure (CHF), response shifts are common in assessing treatment effects. However, few studies focused on potential response shifts in these patients.Materials and methodsData of CHF patient-reported outcome ...
Hong Yang   +9 more
doaj   +1 more source

A Latent Transition Analysis Model for Assessing Change in Cognitive Skills [PDF]

open access: yesEducational and Psychological Measurement, 2015
Latent transition analysis (LTA) was initially developed to provide a means of measuring change in dynamic latent variables. In this article, we illustrate the use of a cognitive diagnostic model, the DINA model, as the measurement model in a LTA, thereby demonstrating a means of analyzing change in cognitive skills over time.
Feiming, Li   +3 more
openaire   +2 more sources

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