Results 51 to 60 of about 24,017,932 (285)

Latent classes of delinquent behaviour associated with criminal social identity among juvenile offenders in Pakistan [PDF]

open access: yes, 2015
© Emerald Group Publishing Limited. Purpose – The purpose of this paper is to examine the number and nature of latent classes of delinquency that exist among male juvenile offenders incarcerated in prisons in Pakistan.
Dhingra, Katie   +8 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A Bayesian semiparametric latent variable model for mixed responses [PDF]

open access: yes, 2006
In this article we introduce a latent variable model (LVM) for mixed ordinal and continuous responses, where covariate effects on the continuous latent variables are modelled through a flexible semiparametric predictor. We extend existing LVM with simple
Raach, Alexander, Fahrmeir, Ludwig
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The mediating role of biological age in the impact of mood instability symptoms on neurodegenerative disease and mortality

open access: yesBMC Medicine
Background Accumulating evidence links mood instability to an increased risk of adverse outcomes, yet its relationship with neurodegenerative diseases remains underexplored.
Junru Wang   +10 more
doaj   +1 more source

Emotion regulation profiles across time: a latent transition analysis

open access: yesInternational Journal of Adolescence and Youth
Difficulties in emotion regulation are associated with mental health problems during adolescence. This study aimed to identify distinct emotion regulation profiles in adolescents, examine potential differences between profiles, and examine transitions ...
Hedvig Andersson   +5 more
doaj   +1 more source

Latent transitions across perceived parental marital conflict and family cohesion profiles in high school students

open access: yesFrontiers in Psychology, 2022
This study aimed to explore the latent profiles across perceived parental marital conflict and family cohesion, as well as the transition patterns within-person and within-sample profiles over time.
Tingting Gao   +14 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru   +13 more
wiley   +1 more source

The development of mathematics expectancy-value profiles during the secondary–tertiary transition into STEM fields

open access: yesInternational Journal of STEM Education
Background To master the secondary–tertiary transition into fields of science, technology, engineering, and mathematics (STEM), academic self-beliefs play a pivotal role, especially those related to learning mathematics. The framework of expectancy-value
Martin Mayerhofer   +2 more
doaj   +1 more source

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