Results 61 to 70 of about 391,534 (273)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

The mediating role of biological age in the impact of mood instability symptoms on neurodegenerative disease and mortality

BMC Medicine
Background Accumulating evidence links mood instability to an increased risk of adverse outcomes, yet its relationship with neurodegenerative diseases remains underexplored.
Junru Wang, Jiahui Zhang, Kai Liu, Jing Wang, Yali Wang, Xiaojun Ma, Zhuoyuan Li, Shulan He, Xiaojuan Liu, Ping Chen, Jiangping Li   +10 more
doaj   +1 more source

Emotion regulation profiles across time: a latent transition analysis

International Journal of Adolescence and Youth
Difficulties in emotion regulation are associated with mental health problems during adolescence. This study aimed to identify distinct emotion regulation profiles in adolescents, examine potential differences between profiles, and examine transitions ...
Hedvig Andersson, Berit Gustafsson, Erik Aspeqvist, Reeta Kankaanpää, Laura Korhonen, Maria Zetterqvist   +5 more
doaj   +1 more source

Stability and Instability of Subjective Well-Being in the Transition from Adolescence to Young Adulthood: Longitudinal Evidence from 20991 Young Australians. [PDF]

PLoS ONE, 2016
PURPOSE:This study assessed the long-term stability and instability of subjective well-being during post-school transition (i.e., transition from adolescence to young adulthood) and evaluated the determinants of transition stability.
Xidan Chen, Andrew Page
doaj   +1 more source

Informative tools for characterizing individual differences in learning: Latent class, latent profile, and latent transition analysis

Learning and Individual Differences, 2017
This article gives an introduction to latent class, latent profile, and latent transition models for researchers interested in investigating individual differences in learning and development. The models allow analyzing how the observed heterogeneity in a group (e.g., individual differences in conceptual knowledge) can be traced back to a mix of ...
Mcmullen , Jake, Schneider, Michael, Edelsbrunner , Peter, Trezise, Kelly, Hickendorff, Marian   +4 more
openaire   +5 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

The development of mathematics expectancy-value profiles during the secondary–tertiary transition into STEM fields

International Journal of STEM Education
Background To master the secondary–tertiary transition into fields of science, technology, engineering, and mathematics (STEM), academic self-beliefs play a pivotal role, especially those related to learning mathematics. The framework of expectancy-value
Martin Mayerhofer, Marko Lüftenegger, Michael Eichmair   +2 more
doaj   +1 more source

Emotional Labor and Occupational Well-Being: Latent Profile Transition Analysis Approach

Frontiers in Psychology, 2018
This study used the latent profile transition analysis (LPTA) to analyze whether emotional labor profiles change across time and how these profiles relate to occupational well-being (i.e., job satisfaction, quality of work life, psychological distress ...
Francis Cheung, Vivian M. C. Lun, Mike W. -L. Cheung   +2 more
doaj   +1 more source

Latent transitions across perceived parental marital conflict and family cohesion profiles in high school students

Frontiers in Psychology, 2022
This study aimed to explore the latent profiles across perceived parental marital conflict and family cohesion, as well as the transition patterns within-person and within-sample profiles over time.
Tingting Gao, Tingting Gao, Tingting Gao, Tingting Gao, Tingting Gao, Leilei Liang, Muzi Li, Muzi Li, Yingying Su, Yingying Su, Songli Mei, Chengchao Zhou, Chengchao Zhou, Xiangfei Meng, Xiangfei Meng   +14 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source