Results 181 to 190 of about 2,066,293 (256)

Entering the Age of Specificity in T Cell Immunity

open access: yesImmunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT The discovery of MHC restriction, the resolution of peptide–MHC structure, and the identification of the T cell receptor gene quickly centered epitope‐level specificity as a core concern of T cell biology. Epitope mapping culminated in functional peptide‐based stimulation assays and tetramer staining, which together provide exquisite ...
Paul G. Thomas
wiley   +1 more source

Bidirectional Synergistic Interaction Between Influenza Virus and SARS‐CoV‐2 in the Postpandemic Era: A Modeling Study

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 10, October 2026.
ABSTRACT Introduction Influenza and COVID‐19 are major respiratory diseases whose co‐circulation dynamics are not fully understood. Surveillance data from the postpandemic period, free from the confounding effects of nonpharmaceutical interventions (NPIs), provide a unique opportunity to study their interactions.
Zhen Qin   +6 more
wiley   +1 more source

PINK1 and PARKIN Deficiency Increases Neuronal Vulnerability to Autoimmune Neuroinflammation Through Mitochondrial Fragmentation in Aged Mice

open access: yesJournal of Neurochemistry, Volume 170, Issue 10, October 2026.
PINK1 and Parkin help protect the nervous system during inflammation. When either protein is missing, autoimmune inflammation becomes more severe and neurons show greater mitochondrial abnormalities and damage, particularly with aging. These findings reveal how defective mitochondrial maintenance can make the brain more vulnerable to inflammatory ...
Davide Cossu   +9 more
wiley   +1 more source

Targeted Tuberculin Testing and Treatment of Latent Tuberculosis Infection [PDF]

open access: yes
This statement provides new recommendations for targeted tuberculin testing and treatment regimens for persons with latent tuberculosis infection (LTBI) and updates previously published guidelines.

core  

In vitro stimulation with nontuberculous mycobacteria induced a stronger cytokine response in leukocytes isolated from individuals with latent tuberculosis compared to those isolated from active tuberculosis or cystic fibrosis patients

open access: yes
Mycobacterium tuberculosis and opportunistic environmental non-tuberculous mycobacteria (NTM) can cause severe infection. Why latent tuberculosis infection advances to active disease, and why some individuals with cystic fibrosis (CF) develop pulmonary ...
Gilljam, Marita   +9 more
core   +1 more source

Latent TB infection : CDC messages and resources : U.S. Preventive Services Task Force Recommendation on Latent Tuberculosis Infection

open access: yes
The U.S. Preventive Services Task Force published a new recommendation to test for latent TB infection in populations at increased risk. The TB community has a unique opportunity to use the announcement of this recommendation to draw attention to latent ...

core  

The blood transcriptional signature for active and latent tuberculosis

open access: yes, 2019
Min Deng,1 Xiao-Dong Lv,2 Zhi-Xian Fang,2 Xin-Sheng Xie,1 Wen-Yu Chen2 1Department of Infectious Diseases, The First Hospital of Jiaxing, The First Affiliated Hospital of Jiaxing University, Jiaxing 314000, China; 2Department of Respiration, The First ...
Lv XD, Xie XS, Deng M, Fang ZX, Chen WY
core  

Evaluation of Latent Tuberculosis Infection Risk in Liver Transplant Recipients. [PDF]

open access: yesJ Clin Med
Öz Kahya M   +7 more
europepmc   +1 more source

Detection of Latent Tuberculosis Infection in Patients with Rheumatological Diseases Who Receive Immunosuppressive Therapy. [PDF]

open access: yesDiagnostics (Basel)
Starshinova A   +8 more
europepmc   +1 more source

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