Results 171 to 180 of about 2,066,293 (256)
Posttranslational Modifications of p62/SQSTM1 in Health and Disease
MedComm, Volume 7, Issue 10, October 2026.Schematic illustration of p62 as a posttranslational modifications (PTMs)‐programmed integrator in homeostasis, pathogenesis, and therapeutic targeting. (Left) Homeostasis: In physiological states, p62, through various PTMs such as phosphorylation, ubiquitination, and acetylation, coordinates essential cellular functions.
Weikai Wang +8 more
wiley +1 more source
Latent tuberculosis infection : a guide for primary health care providers [PDF]
Tuberculosis (TB) is caused by a bacterium called Mycobacterium tuberculosis (M. tuberculosis). Not everyone infected with TB bacteria becomes sick. As a result, two TB-related conditions exist: latent TB infection (LTBI) and TB disease.
core +2 more sources
Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management
MedComm, Volume 7, Issue 10, October 2026.A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley +1 more source
Transmission and pathogenesis of tuberculosis [PDF]
In this module, you will learn about the history of tuberculosis (TB). You will also learn how TB is spread from person to person (transmission) and how TB disease develops in the body (pathogenesis).
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Mucosal‐Associated Invariant T Cells in Health and Disease
MedComm, Volume 7, Issue 10, October 2026.The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
Glutamine Metabolism in Health and Diseases
MedComm, Volume 7, Issue 10, October 2026.Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding +3 more
wiley +1 more source
Small, Volume 22, Issue 59, 22 October 2026.ABSTRACT Bioactive gold plasmonic nanostructures are enabling non‐invasive saliva diagnostics by amplifying weak Raman signals and converting complex biofluid chemistry into information‐rich spectral fingerprints. This Review examines saliva‐based Raman and surface‐enhanced Raman spectroscopy (SERS) integrated with artificial intelligence (AI) from a ...
Ajitesh Dhal +5 more
wiley +1 more source
FASEB BioAdvances, Volume 8, Issue 10, October 2026.Plasma extracellular vesicles (EVs) from individuals with latent (LTB) or active tuberculosis (ATB) exhibit distinct proteomic compositions, reflecting the underlying immunometabolic states of each phase. In LTB, EVs are enriched in proteins associated with tissue remodeling and lipid metabolism, including TGFβ, APOA1, and APOE, which may participate ...
Eliud S.‐Peregrino +13 more
wiley +1 more source
A Multi‐Scale Computational Framework for Anti‐Persister Tuberculosis Drug Discovery
Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.This review presents an integrated QSAR–scaffold design–docking–MD framework for discovering anti‐persister tuberculosis agents active in dormant granuloma‐like conditions. By targeting Mtb bioenergetics and prioritising dual NDH‐2/cytochrome bd oxidase inhibition, the workflow advances rational design of candidates with higher resistance barriers ...
Said Moshawih +6 more
wiley +1 more source
Epileptic Disorders, Volume 28, Issue 5, Page 1679-1682, October 2026.
Ramya Raghupathi
wiley +1 more source