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Diagnosis and management of latent tuberculosis
Current Opinion in Infectious Diseases, 2016Latent tuberculosis infection (LTBI) may affect over two billion individuals and serves as a potential reservoir for future active tuberculosis. The identification and treatment of LTBI in those at highest risk for progression is an essential part of tuberculosis control.Interferon-γ release assays are increasingly used for targeted testing and ...
Meredith L, Turetz, Kevin C, Ma
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Latent Tuberculosis: Is There a Role for Thioridazine?
Recent Patents on Anti-Infective Drug Discovery, 2011Approximately 1/3 of the world's population is infected with Mycobacterium tuberculosis. In the vast majority of cases this results in latent not active disease. Latent disease is defined as a positive reaction to tuberculin antigens but without any further clinical symptoms.
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Rifapentine for the treatment of latent tuberculosis
Expert Review of Clinical Pharmacology, 2016The goal of this article is to review the use of rifapentine in the treatment of latent tuberculosis infection (LTBI). Controlling LTBI is an important part of the global strategy to end the spread of tuberculosis. Rifapentine's potent sterilizing effect against Mycobacterium tuberculosis combined with its long half-life make it an attractive LTBI ...
Eric F, Egelund, Charles A, Peloquin
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Treatment of latent tuberculosis infection
Seminars in Respiratory Infections, 2003Treatment of latent tuberculosis infection (LTBI) is considered an essential component of TB control programs in several industrialized countries and is being used in selected situations in developing countries. In 2000, the American Thoracic Society (ATS) and Centers for Disease Control and Prevention (CDC) published new recommendations on the ...
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Spectrum of latent tuberculosis — existing tests cannot resolve the underlying phenotypes
Nature Reviews Microbiology, 2010Madhukar Pai, Pai Madhukar
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Latent Mycobacterium tuberculosis Infection
New England Journal of Medicine, 2015Haileyesus Getahun +2 more
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Three Months of Rifapentine and Isoniazid for Latent Tuberculosis Infection
New England Journal of Medicine, 2011Timothy R Sterling +2 more
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