Results 91 to 100 of about 1,279,508 (285)

Mesial temporal lobe epilepsy with hippocampal sclerosis: Seizure, neuropsychological, and quality of life outcomes of 100 patients treated with trans‐anterior T1 selective amygdalohippocampectomy

Epileptic Disorders, EarlyView.
Abstract Objective For mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE with HS), laser interstitial thermal therapy has recently been increasingly used. At our institute, however, selective amygdalohippocampectomy by a trans‐anterior T1 subpial approach (trans‐anterior T1 SAH) has been used for MTLE with HS. Here, we examined the seizure,
Naotaka Usui, Hiroshi Ogawa, Akihiko Kondo, Kazumi Matsuda, Mitsuru Hashiguchi, Taro Okumura, Yuuki Ishida, Norihiko Kawaguchi, Takashi Matsudaira, Kentaro Tokumoto, Takuji Nishida, Katsumi Imai   +11 more
wiley   +1 more source

Matrix metalloproteinase 9 (MMP-9) is indispensable for long term potentiation in the central and basal but not in the lateral nucleus of the amygdala

Frontiers in Cellular Neuroscience, 2015
It has been shown that matrix metalloproteinase 9 (MMP-9) is required for synaptic plasticity, learning and memory. In particular, MMP-9 involvement in long-term potentiation (LTP, the model of synaptic plasticity) in the hippocampus and prefrontal ...
Tomasz eGorkiewicz, Tomasz eGorkiewicz, Marcin eBalcerzyk, Marcin eBalcerzyk, Leszek eKaczmarek, Ewelina Anna Knapska   +5 more
doaj   +1 more source

Scalp‐negative medial temporal interictal epileptic discharges alter large‐scale brain networks: A simultaneous high‐density electroencephalographic and intracranial electroencephalographic study

Epilepsia, EarlyView.
Abstract Objective Interictal epileptiform discharges (IEDs) observed on scalp electroencephalography (EEG) serve as a diagnostic hallmark of epilepsy. However, only a small fraction of IEDs recorded by intracranial EEG (iEEG) are detectable on the scalp; the vast majority remain invisible on scalp recordings.
Nicolas Roehri, Pia De Stefano, Laurent Spinelli, Renaud Marquis, Stanislas Lagarde, Shahan Momjian, Margitta Seeck, Serge Vulliemoz   +7 more
wiley   +1 more source

Amygdala size in amyotrophic lateral sclerosis without dementia: an in vivo study using MRI volumetry

BMC Neurology, 2006
Background Evidence for extra-motor involvement in non-demented patients with amyotrophic lateral sclerosis (ALS) has been provided by multiple studies, in particular neuropathological studies have demonstrated neuronal loss in the amygdala.
van Elst Ludger, Pinkhardt Elmar H, Ludolph Albert C, Kassubek Jan   +3 more
doaj   +1 more source

p300/CBP histone acetyltransferase activity is required for newly acquired and reactivated fear memories in the lateral amygdala.

Learning & memory (Cold Spring Harbor, N.Y.), 2013
Modifications in chromatin structure have been widely implicated in memory and cognition, most notably using hippocampal-dependent memory paradigms including object recognition, spatial memory, and contextual fear memory.
S. Maddox, Casey S. Watts, G. Schafe
semanticscholar   +1 more source

Distinct thalamic functional connectivity and volume patterns across focal epilepsies in children: A multimodal neuroimaging study

Epilepsia, EarlyView.
Abstract Objective The thalamus is a key hub in seizure propagation, and its nuclei are emerging targets for neuromodulation. However, the contributions of individual nuclei to epileptic networks remain unclear, particularly in children, who are less studied than adults.
Xiyu Feng, Aswin Chari, Maria H. Eriksson, Freya Prentice, Xiaosong He, Hua Xie, Leigh Sepeta, M. Zubair Tahir, Jonathan D. Clayden, Martin M. Tisdall, Torsten Baldeweg, Rory J. Piper   +11 more
wiley   +1 more source

A model of amygdala function following plastic changes at specific synapses during extinction

Neurobiology of Stress, 2019
The synaptic networks in the amygdala have been the subject of intense interest in recent times, primarily because of the role of this structure in emotion.
Maxwell R. Bennett, Les Farnell, William G. Gibson, Jim Lagopoulos   +3 more
doaj   +1 more source

Long-Term Neural Correlates of Reversible Fear Learning in the Lateral Amygdala

Journal of Neuroscience, 2012
Fear conditioning and extinction are behavioral models that reflect the association and dissociation of environmental cues to aversive outcomes, both known to involve the lateral amygdala (LA). Accordingly, responses of LA neurons to conditioned stimuli (
Bobae An, Ingie Hong, Sukwoo Choi
semanticscholar   +1 more source

Amygdala enlargement associated with remote epileptogenic lesions

Epilepsia, EarlyView.
Abstract Objective To determine the prevalence and possible causes of amygdala enlargement in patients with drug‐resistant temporal lobe epilepsy. Methods Patients were retrospectively identified via a radiology information system and a large language model.
Horst Urbach, Theo Demerath, Alexander Rau, Dirk‐Matthias Altenmüller, Marcel Heers, Samer Elsheikh   +5 more
wiley   +1 more source

Human amygdala nuclei show distinct developmental trajectories from adolescence to adulthood in functional integration with prefrontal circuitry

Cell Reports
Summary: Adolescent neurodevelopment of affective and cognitive control, crucial for healthy functioning and impaired transdiagnostically, is supported by refinements between the amygdala and prefrontal cortex (PFC).
Amar Ojha, Will Foran, Finnegan J. Calabro, Valerie J. Sydnor, Daniel J. Petrie, Ashley C. Parr, Alyssa Famalette, Natalie Phang, Arshia Sista, Shawn F. Sorrells, Beatriz Luna   +10 more
doaj   +1 more source