Results 111 to 120 of about 876,155 (293)
A model of amygdala function following plastic changes at specific synapses during extinction
The synaptic networks in the amygdala have been the subject of intense interest in recent times, primarily because of the role of this structure in emotion.
Maxwell R. Bennett +3 more
doaj +1 more source
Shown in the upper bar graphs are the comparisons in optical density (mean ± SE) of immunostaining for glial fibrillary acidic protein (GFAP) and myelin basic protein (MBP) between ipsilateral and contralateral sides of the amygdala.
Seth P. Finklestein (2213509) +9 more
core +1 more source
Limited sex‐specific structural alterations across common epilepsies: A worldwide ENIGMA study
Abstract Objective Epilepsy is characterized by widespread cortical and subcortical structural alterations beyond the epileptic zone. Importantly, the clinical manifestation of epilepsy, including seizure types, psychiatric comorbidities, and treatment responses, has been shown to differ between sexes. However, sex differences in structural alterations
Huantao Wen +68 more
wiley +1 more source
Basolateral amygdala volume in affective disorders using 7T MRI in vivo
BackgroundThe basolateral complex of the amygdala is a crucial neurobiological site for Pavlovian conditioning. Investigations into volumetric alterations of the basolateral amygdala in individuals with major depressive disorder (MDD) have yielded ...
Benedikt Kürzinger +8 more
doaj +1 more source
Background: Subcortical nuclei are important components in the pathology model of obsessive-compulsive disorder (OCD), and subregions of these structures subserve different functions that may distinctively contribute to OCD symptoms.
Lianqing Zhang +12 more
doaj +1 more source
Theory of mind: A cognitive endophenotype of juvenile myoclonic epilepsy?
Abstract Objective Juvenile myoclonic epilepsy (JME), the most common idiopathic generalized epilepsy, is associated with neuropsychological and psychiatric comorbidities, including social cognition and theory of mind (ToM) deficits. The interplay between clinical features, social cognition, and their neural and genetic substrates remains poorly ...
Bernardo Crespo‐Pimentel +13 more
wiley +1 more source
Activation of GABAARs in the lateral nucleus of the amygdala (LA), a key site of plasticity underlying fear learning, impairs fear learning. The role of GABACRs in the LA and other brain areas is poorly understood.
Catarina Cunha +5 more
doaj +1 more source
Abstract Objective RAP‐219, a potent selective negative allosteric modulator (NAM) of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) associated with γ8 transmembrane AMPAR regulatory protein (TARPγ8), is in phase 3 development for refractory focal epilepsy. This study was undertaken to assess efficacy and motor function following
Jose A. Matta +5 more
wiley +1 more source
Palmitoylation has been implicated in learning and memory processes, yet its precise role and underlying mechanisms remain poorly understood. Here, we report a novel role of palmitoylation in regulating amygdalar synaptic plasticity and fear memory ...
Zu‐Cheng Shen +11 more
doaj +1 more source

