Results 111 to 120 of about 876,155 (293)

A model of amygdala function following plastic changes at specific synapses during extinction

open access: yesNeurobiology of Stress, 2019
The synaptic networks in the amygdala have been the subject of intense interest in recent times, primarily because of the role of this structure in emotion.
Maxwell R. Bennett   +3 more
doaj   +1 more source

Injury to the Amygdala.

open access: yes, 2016
Shown in the upper bar graphs are the comparisons in optical density (mean ± SE) of immunostaining for glial fibrillary acidic protein (GFAP) and myelin basic protein (MBP) between ipsilateral and contralateral sides of the amygdala.
Seth P. Finklestein (2213509)   +9 more
core   +1 more source

Limited sex‐specific structural alterations across common epilepsies: A worldwide ENIGMA study

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is characterized by widespread cortical and subcortical structural alterations beyond the epileptic zone. Importantly, the clinical manifestation of epilepsy, including seizure types, psychiatric comorbidities, and treatment responses, has been shown to differ between sexes. However, sex differences in structural alterations
Huantao Wen   +68 more
wiley   +1 more source

Basolateral amygdala volume in affective disorders using 7T MRI in vivo

open access: yesFrontiers in Psychiatry
BackgroundThe basolateral complex of the amygdala is a crucial neurobiological site for Pavlovian conditioning. Investigations into volumetric alterations of the basolateral amygdala in individuals with major depressive disorder (MDD) have yielded ...
Benedikt Kürzinger   +8 more
doaj   +1 more source

Characteristic alteration of subcortical nuclei shape in medication-free patients with obsessive-compulsive disorder

open access: yesNeuroImage: Clinical, 2019
Background: Subcortical nuclei are important components in the pathology model of obsessive-compulsive disorder (OCD), and subregions of these structures subserve different functions that may distinctively contribute to OCD symptoms.
Lianqing Zhang   +12 more
doaj   +1 more source

Theory of mind: A cognitive endophenotype of juvenile myoclonic epilepsy?

open access: yesEpilepsia, EarlyView.
Abstract Objective Juvenile myoclonic epilepsy (JME), the most common idiopathic generalized epilepsy, is associated with neuropsychological and psychiatric comorbidities, including social cognition and theory of mind (ToM) deficits. The interplay between clinical features, social cognition, and their neural and genetic substrates remains poorly ...
Bernardo Crespo‐Pimentel   +13 more
wiley   +1 more source

GABAC receptors in the lateral amygdala: a possible novel target for the treatment of fear and anxiety disorders?

open access: yesFrontiers in Behavioral Neuroscience, 2010
Activation of GABAARs in the lateral nucleus of the amygdala (LA), a key site of plasticity underlying fear learning, impairs fear learning. The role of GABACRs in the LA and other brain areas is poorly understood.
Catarina Cunha   +5 more
doaj   +1 more source

Temporal lobe epilepsy with bilateral amygdala enlargement mimicking behavioral variant frontotemporal dementia

open access: yes
Epileptic Disorders, EarlyView.
Kentaro Tokumoto   +7 more
wiley   +1 more source

Selective γ8 transmembrane α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor regulatory protein negative allosteric modulators: Efficacy in preclinical antiseizure models

open access: yesEpilepsia, EarlyView.
Abstract Objective RAP‐219, a potent selective negative allosteric modulator (NAM) of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) associated with γ8 transmembrane AMPAR regulatory protein (TARPγ8), is in phase 3 development for refractory focal epilepsy. This study was undertaken to assess efficacy and motor function following
Jose A. Matta   +5 more
wiley   +1 more source

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

open access: yesAdvanced Science
Palmitoylation has been implicated in learning and memory processes, yet its precise role and underlying mechanisms remain poorly understood. Here, we report a novel role of palmitoylation in regulating amygdalar synaptic plasticity and fear memory ...
Zu‐Cheng Shen   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy