Results 181 to 190 of about 58,666 (254)
The Microbiota Shapes Central Nervous System Myelination in Early Life
Advanced Science, Volume 13, Issue 14, 9 March 2026.Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch +13 more
wiley +1 more source
Advanced Science, Volume 13, Issue 14, 9 March 2026.This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen +8 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION Cerebral small vessel disease (CSVD) contributes to the development of Alzheimer's disease (AD) dementia and co‐occurs with AD‐associated proteinopathies. However, how sex modulates the interaction between CSVD and AD‐associated proteinopathies in the medial temporal lobe (MTL) remains unclear.
Francesco Bax +14 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION The locus coeruleus (LC), the first region to contain tau pathology in Alzheimer's disease (AD), releases norepinephrine, which has a neuroprotective role. We examined whether LC integrity relates to whole‐brain integrity and how AD biomarkers may moderate this relationship.
Emilie Foyard +9 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION Clarifying relationships between amyloid, tau, and cognition is crucial to understanding dementia risk, but has been mainly performed in non‐Hispanic White (NHW) participants. It is unknown whether findings are generalizable to other ethnoracial groups.
Koral V. Wheeler +49 more
wiley +1 more source
Longitudinal association between sleep and Alzheimer's pathology
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION Since sleep disturbance is a modifiable risk factor for Alzheimer's disease (AD), we tested associations between sleep and AD pathology in cognitively unimpaired (CU) persons. METHODS We included 223 participants from the PREVENT‐AD cohort with self‐reported measures of sleep, objective actigraphy measures of sleep, and positron ...
Bery Mohammediyan +13 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION Microglial activation can either support neuronal function or exacerbate damage, contributing to Alzheimer's disease (AD) progression. We investigated spatial relationships among microglial activation, neuronal health, and amyloid beta (Aβ) in the AD spectrum.
Yaoyu Zhang +20 more
wiley +1 more source
Implication of the thalamus in sleep alterations observed in Alzheimer's disease
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Alzheimer's disease (AD), the most common neurodegenerative disorder, is frequently accompanied by sleep disturbances. Alterations of sleep, in both quality and quantity, contribute to the progression of AD neuropathology. The thalamus, through its diverse nuclei, plays a central role in sleep regulation and sleep‐dependent memory ...
Carla Burnet‐Merlin +2 more
wiley +1 more source
Arp2/3 and VASP Are Essential for Fear Memory Formation in Lateral Amygdala. [PDF]
eNeuro, 2016 Basu S, Kustanovich I, Lamprecht R.
europepmc +1 more source
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION Hippocampal subfields are vulnerable to the transactive response DNA‐binding protein of 43 kDa (TDP‐43) and tau in primary age‐related tauopathy (PART). Geometry‐based morphometric analysis can improve the detection of structural changes in the hippocampus.
Hossam Youssef +6 more
wiley +1 more source