Results 161 to 170 of about 876,155 (293)
Abstract Objective Olfactory function is influenced by nasal airflow dynamics and anatomical variations within the nasal cavity. This narrative review evaluates how nasal anatomy and airflow relate to olfactory outcomes, with a particular focus on olfactory changes following functional nasal surgery. Data Sources PubMed.
Joshua Ferreira +3 more
wiley +1 more source
Potential value of slow‐wave sleep in management of chronic insomnia disorder
Abstract Chronic insomnia disorder (CID), acknowledged as the most common sleep disorder, has traditionally been diagnosed and managed with a focus on reducing sleep onset latency and extending total sleep duration. However, the critical importance of slow‐wave sleep (SWS), a key indicator of objective sleep quality, has been largely overlooked in ...
Liping Zhang +4 more
wiley +1 more source
Excitatory synaptic transmission in the lateral and central amygdala
The amygdala plays a major role in the acquisition and expression of fear conditioning. NMDA receptor-dependent synaptic plasticity within the basolateral amygdala has been proposed to underlie the acquisition and possible storage of fear memories.
Sah, Pankaj, Lopez de Armentia, Mikel
core
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer +16 more
wiley +1 more source
Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions
An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich +5 more
wiley +1 more source
Artificial intelligence–based 3D segmentation of tangle‐associated TDP‐43 in neurodegeneration
Multiplex immunostaining of anti‐phosphorylated TDP‐43, tau (AT8, pS396, TauC3, MN423, GT38), and Thioflavin S combined with AI‐based object recognition, reconstruction, and TAT maturation analysis pipeline in limbic regions revealed that distinct aggregation and tangle maturation patterns underscored region‐specific dynamics in the neurodegenerative ...
Gokhan Uruk +6 more
wiley +1 more source
Chronic traumatic encephalopathy in a neuropathologically confirmed Creutzfeldt–Jakob disease cohort
Systematic neuropathological screening of 212 patients with Creutzfeldt–Jakob disease (55% women) identified chronic traumatic encephalopathy in three cases (1.4%), all men with a history of contact sports. These findings represent the first neuropathologically confirmed chronic traumatic encephalopathy cases reported in Spain.
Lluc Bertran +13 more
wiley +1 more source
Amygdala vulnerability in Pick disease with discrete frontotemporal dementia syndromes
Clinicopathological characterization of the amygdala in FTLD‐tau. Amygdala vulnerability in FTLD‐tauopathies is defined by elevated neuroinflammation and tau in 3R versus 4R subtypes, and greater neuroinflammation in bvFTD versus PPA. In Pick disease, bvFTD and PPA converge neuropsychiatrically over time, and intracellular tau correlates with increased
Rachel Keszycki +13 more
wiley +1 more source
An insular cortex to lateral amygdala pathway in fear learning
Palchaudhuri S +3 more
europepmc +1 more source
Low-threshold spiking interneurons perform feedback inhibition in the lateral amygdala. [PDF]
Ünal ÇT, Ünal B, Bolton MM.
europepmc +1 more source

