Divergent input patterns to the central lateral amygdala play a duet in fear memory formation. [PDF]
Gao JH +9 more
europepmc +1 more source
Preponderance of Late-spiking Neurons in Rat Lateral Amygdala
Whole-cell recordings from rat lateral amygdala (LA) revealed two populations of principal neurons, that have similar pyramid-like morphologies but differing in firing pattern: late-spiking (LS, 66%) and regular-spiking (RS, 34%).
McNay, Dr Ewan C., Brown, Dr Thomas H.
core
Investigation of the mechanisms and modulation of irinotecan‐induced emesis in Suncus murinus
Abstract Background and Purpose Irinotecan is a widely used chemotherapeutic agent that frequently causes nausea and emesis. Its emetic mechanism of action is poorly understood and the choice of drugs to reduce nausea and emesis is largely empirical. Experimental Approach Using Suncus murinus, we examined (i) the dose–response and temporal profile of ...
Zengbing Lu +7 more
wiley +1 more source
Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala. [PDF]
Matsumoto Y +7 more
europepmc +1 more source
Novel targets in headache: A narrative review
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra +5 more
wiley +1 more source
Fear learning induces synaptic potentiation between engram neurons in the rat lateral amygdala. [PDF]
Abatis M +9 more
europepmc +1 more source
Proliferation of the term “emotion dysregulation” in child psychopathology parallels the growing interest in processes that influence negative emotional reactivity. While it commonly refers to a clinical phenotype where intense anger leads to behavioral dyscontrol, the term implies etiology because anything that is dysregulated requires an impaired ...
Joseph C. Blader +2 more
wiley +1 more source
Corticotropin-Releasing Factor Receptor-1 Neurons in the Lateral Amygdala Display Selective Sensitivity to Acute and Chronic Ethanol Exposure. [PDF]
Agoglia AE +10 more
europepmc +1 more source
Cognitive reappraisal modulates neural responses to aversive sensory stimulation in autistic youth
Background Sensory over‐responsivity (SOR) is highly prevalent and impairing in autism spectrum disorder (ASD). SOR has been associated with sensory‐limbic hyperresponsivity and reduced prefrontal top‐down regulation during sensory stimulation. There are few evidence‐based treatments for SOR, but cognitive reappraisal, an emotion regulation strategy ...
Urvi T. Shah +7 more
wiley +1 more source
Microglial activation in the lateral amygdala promotes anxiety-like behaviors in mice with chronic moderate noise exposure. [PDF]
Peng X +12 more
europepmc +1 more source

