Results 201 to 210 of about 876,155 (293)

Insula–cerebellar functional connectivity associated with somatic symptoms in mood disorders: Differential patterns and longitudinal evidence in major depressive disorder

Psychiatry and Clinical Neurosciences, EarlyView.
Aim This study aimed to identify the resting‐state functional connectivity (rsFC) of insula subregions associated with nonspecific somatic symptoms in mood disorders and to examine whether these connections are state‐dependent. Methods In Phase 1, seed‐based rsFC analyses were performed using 12 insula subregions from the Brainnetome Atlas in patients ...
Shin Hattori, Toshiharu Kamishikiryo, Alan S. R. Fermin, Yoichiro Matsumoto, Yuki Mitsuyama, Eri Itai, Yoshikazu Masuda, Go Okada   +7 more
wiley   +1 more source

Transdiagnostic patterns of electroencephalography (EEG)‐derived aperiodic activity across schizophrenia‐spectrum, bipolar, and depressive disorders: A systematic review

Psychiatry and Clinical Neurosciences, EarlyView.
Aperiodic electroencephalographic activity is proposed as a scalable marker of cortical population dynamics relevant to excitation–inhibition balance. However, it remains unclear whether aperiodic parameters represent disorder‐specific abnormalities or context‐sensitive indices of clinically relevant brain states.
Gia Han Le, Sabrina Wong, Sara Di Luch, Diana K. Orsini, Shreya Vasudeva, Sri Mahavir Agarwal, Cristian‐Daniel Llach, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Altered prefrontal suppression of striatal activity during intrusive images in obsessive‐compulsive disorder

Psychiatry and Clinical Neurosciences, EarlyView.
Background Current models of obsessive‐compulsive disorder (OCD) emphasize dysfunction in frontostriatal circuits that support flexible behavioral control, leading to impulsive and compulsive actions. However, how these disruptions contribute to obsessions and intrusive thoughts remains poorly understood.
Anaïs Vandevelde, Sonia Dollfus, Pierre Gagnepain   +2 more
wiley   +1 more source

Lower cerebral blood flow but not cerebrovascular response in elastin haploinsufficient mice

Experimental Physiology, EarlyView.
Abstract Elastin insufficiency is associated with structural differences in the large elastic arteries and cerebral artery dysfunction. However, previous studies have not assessed potential sex differences in cerebrovascular function. We measured cerebral blood flow (CBF) using arterial spin labeling MRI at rest and in response to hypercapnia challenge
Abigail E. Cullen, Emily H. Reeve, Nick R. Winder, Grant D. Henson, Nayantara Arora, Thomas Leonhardt, Ainsley Hogan, Sahana Krishna Kumaran, Naly Setthavonsack, Victoria Krajbich, Art Riddle, Benjamin Zimmerman, Nabil J. Alkayed, Martin M. Pike, Randall L. Woltjer, Ashley E. Walker   +15 more
wiley   +1 more source

Mitochondrial capacities and quality control following short‐ and long‐term weight restoration after simulated anorexia nervosa

Experimental Physiology, EarlyView.
Abstract Anorexia nervosa (AN) is a psychiatric disorder characterized by prolonged caloric restriction and skeletal muscle atrophy. Mitochondrial health is a key mediator of muscle function, yet the role of mitochondria during AN and following weight regain has not been investigated. The objective of this study was to evaluate mitochondrial capacities
Megan E. Rosa‐Caldwell, Toby L. Chambers, Lauren Breithaupt, Ruqaiza Muhyudin, Patience Salvalina Okoto, Sadie R. Thompson, Emily E. Rothacker, Claire Greenhill, Katie A. Wood, Kevin A. Murach, Sarah H. White‐Springer, Ursula B. Kaiser, Seward B. Rutkove   +12 more
wiley   +1 more source

Synapsin I Controls Synaptic Maturation of Long-Range Projections in the Lateral Amygdala in a Targeted Selective Fashion. [PDF]

Front Cell Neurosci, 2019
Lugarà E, De Fusco A, Lignani G, Benfenati F, Humeau Y.   +4 more
europepmc   +1 more source

Placebo and nocebo effects on pain through the lens of the predictive brain: Neurobiological mechanisms and translational implications

Experimental Physiology, EarlyView.
Abstract Placebo and nocebo effects on pain provide a model for investigating how cognitive and contextual factors modulate the physiological processes underlying nociception and its regulation. However, existing accounts remain fragmented and lack a unifying mechanistic framework linking brain, behaviour and autonomic responses.
Denisa Adina Zamfira, Tommaso Fassina, Kamil Zaworski, Elisa Carlino, Giacomo Rossettini   +4 more
wiley   +1 more source

Prenatal air pollution exposure is associated with altered neurodevelopmental outcomes in early childhood

The Journal of Physiology, EarlyView.
Abstract figure legend This study examined the effect of modelled maternal air pollution exposure during gestation on neurodevelopment in a community cohort of 498 toddlers recruited from Greater London, UK. Higher 1st trimester exposure to particulate matter and nitrogen dioxide was associated with lower language scores at 18 months adjusting for ...
Alexandra F. Bonthrone, Brendan Bos, Ben Barratt, Hoi Ching Olina Pang, Sean Beevers, Andrew Chew, Shona Falconer, Joseph V. Hajnal, Frank J. Kelly, Chiara Nosarti, A. David Edwards, Serena J. Counsell   +11 more
wiley   +1 more source

SNARE Complex-Associated Proteins in the Lateral Amygdala of Macaca mulatta Following Long-Term Ethanol Drinking. [PDF]

Alcohol Clin Exp Res, 2018
Alexander NJ, Rau AR, Jimenez VA, Daunais JB, Grant KA, McCool BA.   +5 more
europepmc   +1 more source

Blood Biomarkers of Alzheimer's Disease and Patterns of Structural Brain Changes in the Community

Annals of Neurology, Volume 100, Issue 5, Page 987-997, November 2026.
Objective We aimed to investigate the associations between Alzheimer's disease (AD)‐related blood biomarkers and changes in brain volumes and cerebrovascular burden in community‐dwelling older adults. Methods We included 361 dementia‐free participants with a Mini‐Mental State Examination (MMSE) score ≥ 27 and without prior cerebrovascular events from a
Martina Valletta, Davide Liborio Vetrano, Erika J. Laukka, Grégoria Kalpouzos, Javier Oltra, Debora Rizzuto, Marco Canevelli, Claudia Fredolini, Chengxuan Qiu, Bengt Winblad, Laura Fratiglioni, Giulia Grande   +11 more
wiley   +1 more source