Results 11 to 20 of about 1,279,508 (285)
Intrinsic Circuits in the Lateral Central Amygdala [PDF]
eneuro, 2017 Network activity in the lateral central amygdala (CeL) plays a crucial role in fear learning and emotional processing. However, the local circuits of the CeL are not fully understood and have only recently begun to be explored in detail.
S. Hunt +4 more
semanticscholar +5 more sources
Smaller volumes in the lateral and basal nuclei of the amygdala in patients with panic disorder. [PDF]
PLoS ONE, 2018 The amygdala plays an important functional role in fear and anxiety. Abnormalities in the amygdala are believed to be involved in the neurobiological basis of panic disorder (PD).
Takeshi Asami +6 more
doaj +2 more sources
Reverse engineering information processing in lateral amygdala during auditory tones. [PDF]
Int IEEE EMBS Conf Neural Eng, 2023 Learning in the mammalian lateral amygdala (LA) during auditory fear conditioning (tone - foot shock pairing), one form of associative learning, requires N-methyl-D-aspartate (NMDA) receptor-dependent plasticity. Despite this fact being known for more than two decades, the biophysical details related to signal flow and the involvement of the ...
Glickert G, Latimer B, Sah P, Nair SS.
europepmc +3 more sources
Dynamic coding of predatory information between the prelimbic cortex and lateral amygdala in foraging rats. [PDF]
Sci Adv, 2018 We report how the brain codes predatory threat information to guide and shape foraging behaviors in rats. Predation is considered a major selective pressure in the evolution of fear, but the neurophysiology of predator-induced fear is unknown.
Kim EJ +5 more
europepmc +2 more sources
Role of lateral amygdala calstabin2 in regulation of fear memory. [PDF]
Mol Brain, 2020 AbstractCalstabin2, also named FK506 binding protein 12.6 (FKBP12.6), is a subunit of ryanodine receptor subtype 2 (RyR2) macromolecular complex, an intracellular calcium channel. Studies from our and other’s lab have shown that hippocampal calstabin2 regulates spatial memory.
Han RW +8 more
europepmc +5 more sources
An insular cortex to lateral amygdala pathway in fear learning
, 2023 Animals are capable of evaluating sensory cues for possible threats and adapting their behaviours accordingly. Fear learning is an evolutionarily conserved behaviour crucial for animal survival, during which sensory percepts with a negative reinforcing quality, also called unconditioned stimuli (US), influence the valence of initially neutral sensory ...
Palchaudhuri S +3 more
europepmc +2 more sources
Frontiers in Neuroscience, 2015 In social mammals, the presence of an affiliative conspecific reduces stress responses, a phenomenon referred to as ‘social buffering’. In a previous study, we found that the presence of a conspecific animal ameliorated a variety of stress responses to ...
Felipe eFuzzo +5 more
doaj +2 more sources
Loss of the Mecp2 gene in parvalbumin interneurons leads to an inhibitory deficit in the amygdala and affects its functional connectivity [PDF]
Molecular AutismBackground The MECP2 gene is located on the X chromosome and encodes a methyl-CpG-binding protein 2 involved in transcriptional regulation. Loss-of-function mutations in the MECP2 gene lead to Rett syndrome, a severe neurodevelopmental disorder.
Maj Liiwand +6 more
doaj +2 more sources
Scientific Reports, 2023 The amygdala plays a role in emotion, learning, and memory and has been implicated in behavioral disorders. Better understanding of the amygdala circuitry is crucial to develop new therapies for these disorders.
Josue M. Avecillas-Chasin +6 more
doaj +1 more source
Frontiers in Human Neuroscience, 2022 We examined amygdala subregion volumes in patients with a first episode of major depression (MD) and in healthy subjects. Covariate-adjusted linear regression was performed to compare the MD and healthy groups, and adjustments for age, gender, and total ...
Hirofumi Tesen +7 more
doaj +1 more source