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Hyperconnectivity of the lateral amygdala in long-term methamphetamine abstainers negatively correlated with withdrawal duration [PDF]

open access: yesFrontiers in Pharmacology, 2023
Introduction: Several studies have reported structural and functional abnormalities of the amygdala caused by methamphetamine addiction. However, it is unknown whether abnormalities in amygdala function persist in long-term methamphetamine abstainers ...
Yifan Li   +13 more
doaj   +2 more sources

The entorhinal cortex modulates trace fear memory formation and neuroplasticity in the mouse lateral amygdala via cholecystokinin [PDF]

open access: yeseLife, 2021
Although fear memory formation is essential for survival and fear-related mental disorders, the neural circuitry and mechanism are incompletely understood. Here, we utilized trace fear conditioning to study the formation of trace fear memory in mice.
Hemin Feng   +4 more
doaj   +2 more sources

Pavlovian fear conditioning activates a common pattern of neurons in the lateral amygdala of individual brains. [PDF]

open access: yesPLoS ONE, 2011
Understanding the physical encoding of a memory (the engram) is a fundamental question in neuroscience. Although it has been established that the lateral amygdala is a key site for encoding associative fear memory, it is currently unclear whether the ...
Hadley C Bergstrom   +2 more
doaj   +4 more sources

Synaptic and intrinsic plasticity within overlapping lateral amygdala ensembles following fear conditioning [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2023
IntroductionNew learning results in modulation of intrinsic plasticity in the underlying brain regions. Such changes in intrinsic plasticity can influence allocation and encoding of future memories such that new memories encoded during the period of ...
Megha Sehgal   +3 more
doaj   +2 more sources

Smaller volumes in the lateral and basal nuclei of the amygdala in patients with panic disorder. [PDF]

open access: yesPLoS ONE, 2018
The amygdala plays an important functional role in fear and anxiety. Abnormalities in the amygdala are believed to be involved in the neurobiological basis of panic disorder (PD).
Takeshi Asami   +6 more
doaj   +2 more sources

Connectivity-based parcellation of the amygdala and identification of its main white matter connections

open access: yesScientific Reports, 2023
The amygdala plays a role in emotion, learning, and memory and has been implicated in behavioral disorders. Better understanding of the amygdala circuitry is crucial to develop new therapies for these disorders.
Josue M. Avecillas-Chasin   +6 more
doaj   +1 more source

Volume of Amygdala Subregions and Clinical Manifestations in Patients With First-Episode, Drug-Naïve Major Depression

open access: yesFrontiers in Human Neuroscience, 2022
We examined amygdala subregion volumes in patients with a first episode of major depression (MD) and in healthy subjects. Covariate-adjusted linear regression was performed to compare the MD and healthy groups, and adjustments for age, gender, and total ...
Hirofumi Tesen   +7 more
doaj   +1 more source

Surface morphology of amygdala is associated with trait anxiety. [PDF]

open access: yesPLoS ONE, 2012
Previous neuroimaging studies have suggested a role of amygdala in trait anxiety level, in which amygdala was typically treated as a whole. To date, it remains unknown whether the morphology of specific subregions of amygdala are associated with trait ...
Shuyu Li   +7 more
doaj   +1 more source

MRI data confirm the selective involvement of thalamic and amygdalar nuclei in amyotrophic lateral sclerosis and primary lateral sclerosis

open access: yesData in Brief, 2020
A standardised imaging protocol was implemented to evaluate disease burden in specific thalamic and amygdalar nuclei in 133 carefully phenotyped and genotyped motor neuron disease patients.
Rangariroyashe H. Chipika   +15 more
doaj   +1 more source

Gastrin-releasing peptide signaling plays a limited and subtle role in amygdala physiology and aversive memory. [PDF]

open access: yesPLoS ONE, 2012
Links between synaptic plasticity in the lateral amygdala (LA) and Pavlovian fear learning are well established. Neuropeptides including gastrin-releasing peptide (GRP) can modulate LA function. GRP increases inhibition in the LA and mice lacking the GRP
Frederique Chaperon   +10 more
doaj   +1 more source

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