Results 21 to 30 of about 1,677,295 (274)

Reliability Analysis of Intersection Sight Distance at Roundabouts

Infrastructures, 2020
This paper presents a reliability-based method for the design of intersection sight distance (ISD) at traffic roundabouts using the linear and nonlinear deceleration profiles of the entry vehicles.
Said M. Easa, Yang Ma, Shixu Liu, Yanqun Yang, Shriniwas Arkatkar   +4 more
doaj   +1 more source

Thioridazine reverts the phenotype in cellular and Drosophila models of amyotrophic lateral sclerosis by enhancing TDP-43 aggregate clearance.

Neurobiology of Disease, 2021
Brain inclusions mainly composed of misfolded and aggregated TAR DNA binding protein 43 (TDP-43), are characteristic hallmarks of amyotrophic lateral sclerosis (ALS).
Lucía Cragnaz, Greta Spinelli, Laura De Conti, Emilie A. Bureau, J. Brownlees, F. Feiguin, Valentina Romano, N. Skoko, Raffaella Klima, C. Kettleborough, F. Baralle, Marco Baralle   +11 more
semanticscholar   +1 more source

The safety benefits added by lateral roadside clearance to urban streets [PDF]

WIT Transactions on The Built Environment, 2009
This research will illustrate that, within an urban setting and on curbed roadways of similar conditions, a minimum clear zone setback distance of ten feet is probably not necessary. The distance from the edge of the roadway to a fixed object is known as the clear zone, or lateral offset.
T. H. Maze, C. Sax, N. R. Hawkins
openaire   +1 more source

Factors Influencing Presence or Absence of Laterality During Pharyngeal Bolus Clearance

Perspectives of the ASHA Special Interest Groups, 2020
Purpose The aim of this study was to identify factors influencing pharyngeal laterality of bolus clearance through the pharyngoesophageal segment. Method Two swallowing trials (5-ml nectar-thickened liquid and 5-ml pudding) administered in the anteroposterior viewing plane during ...
Kendrea L, Garand, Taylor, Thomas, Rajarshi, Dey   +2 more
openaire   +3 more sources

LATERAL PERCUTANEOUS NEPHROLITHOTOMY: A CASE SERIES

Jurnal Urologi Indonesia, 2020
Objective: To report our experience on lateral PCNL in the management of complex kidney stone in patients with many morbidities. Case(s) Presentation: In our hospital, there were 2 cases of incomplete stone clearance after PCNL which underwent lateral ...
Zola Wijayanti, Sawkar Vijay Pramod
doaj   +1 more source

Truncation-Driven Lateral Association of α-Synuclein Hinders Amyloid Clearance by the Hsp70-Based Disaggregase [PDF]

International Journal of Molecular Sciences, 2021
The aggregation of α-synuclein is the hallmark of a collective of neurodegenerative disorders known as synucleinopathies. The tendency to aggregate of this protein, the toxicity of its aggregation intermediates and the ability of the cellular protein quality control system to clear these intermediates seems to be regulated, among other factors, by post-
Aitor Franco, Jorge Cuéllar, José Ángel Fernández-Higuero, Igor de la Arada, Natalia Orozco, José M. Valpuesta, Adelina Prado, Arturo Muga   +7 more
openaire   +4 more sources

Influence of roadway geometric elements on driver behavior when overtaking bicycles on rural roads

Journal of Traffic and Transportation Engineering (English ed. Online), 2014
The objective of this research was to determine what influence geometric design elements of roadway may have on driver behavior during the overtaking maneuver.
Jeremy R. Chapman, David A. Noyce
doaj   +1 more source

Early itch relief with upadacitinib predicts later skin clearance in Atopic dermatitis

Journal of Dermatological Treatment, 2023
Though Janus kinase inhibitors such as upadacitinib rapidly relieve itch in atopic dermatitis (AD) patients, how early itch relief impacts later skin clearance is not examined.This study aims to determine if early itch relief by upadacitinib could predict complete skin clearance in later phases.This retrospective study involved 105 patients with ...
Teppei Hagino, Mai Yoshida, Risa Hamada, Hidehisa Saeki, Eita Fujimoto, Naoko Kanda   +5 more
openaire   +3 more sources

Characteristics of lateral vehicular interactions in heterogeneous traffic with weak lane discipline

Journal of Modern Transportation, 2017
Heterogeneous traffic conditions prevail in developing countries. Vehicles maintain weak lane discipline which increases lateral interactions of vehicles significantly.
Anuj Kishor Budhkar, Akhilesh Kumar Maurya   +1 more
doaj   +1 more source

Association between CYP1A2 activity and riluzole clearance in patients with amyotrophic lateral sclerosis [PDF]

British Journal of Clinical Pharmacology, 2005
AimsRiluzole is used in a fixed dosing schedule of 50 mg twice daily to treat patients with amyotropic lateral sclerosis (ALS), one form of motor neurone disease. The large variability in the pharmacokinetics of riluzole may be a factor contributing to its limited therapeutic benefit.
van Kan, H. J. M., Groeneveld, G. J., Kalmijn, S., Spieksma, M., van den Berg, L. H., Guchelaar, H. J.   +5 more
openaire   +2 more sources