Results 31 to 40 of about 1,677,295 (274)

Glucose clearance and uptake is increased in the SOD1G93A mouse model of amyotrophic lateral sclerosis through an insulin-independent mechanism

open access: yesbioRxiv, 2020
Metabolic disturbances are associated with the progression of the neurodegenerative disorder, amyotrophic lateral sclerosis (ALS), however the molecular events that drive energy imbalances in ALS are not completely understood.
Tanya S. McDonald   +4 more
semanticscholar   +1 more source

Evaluation the behavior of seismic bracing connections based on clearance [PDF]

open access: yesJournal of Structural and Construction Engineering, 2018
Today one of the most common systems for resisting lateral forces (wind and earthquake) is special concentrically braced frames (SCBF). Out of plane buckling in compression causes large inelastic flexural deformations in gusset plate.
Mojtaba Akrami, Ehsan Dehghani
doaj   +1 more source

Single Incision Lateral Mammoplasty as an Oncoplastic Technique in Laterally Located Breast Cancer; a Prospective Controlled Study [PDF]

open access: yesAin-Shams Journal of Surgery, 2023
Background: More than half of breast cancer lesions occur in the outer quadrant, mostly diagnosed in early stages. Cases with late stages are usually directed to total mastectomy and/or axillary clearance.
Sherief Mohsen   +2 more
doaj   +1 more source

The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy

open access: yesCell Reports, 2023
SUMMARY In response to lysosomal damage, cells engage several quality-control mechanisms, including the selective isolation and degradation of damaged lysosomes by lysophagy. Here, we report that the selective autophagy adaptor SQSTM1/p62 is recruited to
Elizabeth R. Gallagher, E. Holzbaur
semanticscholar   +1 more source

Three-dimensional foot trajectory in female patients with end-stage hip osteoarthritis during walking

open access: yesScientific Reports, 2022
Osteoarthritis (OA) is a risk factor for falls. To decrease the fall risk, it is important to evaluate the detailed features of the gait of patients with OA.
Yu Kiko   +5 more
doaj   +1 more source

Lateral percutaneous nephrolithotomy: A safe and effective surgical approach

open access: yesIndian Journal of Urology, 2018
Introduction: Percutaneous nephrolithotomy (PCNL) is traditionally performed with the patient in the prone position for large renal calculi. However, anesthetic limitations exist with the prone position.
Jonathan Jian Wei Gan   +3 more
doaj   +1 more source

Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome.

open access: yesCell Reports, 2023
Expansion of the hexanucleotide repeat GGGGCC in the C9orf72 gene is the most common genetic factor in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Xiaoqiu Shu   +11 more
semanticscholar   +1 more source

Influence of the background activity region selection on the measurement of glomerular filtration rate using the Gates method [PDF]

open access: yesVojnosanitetski Pregled, 2008
Background/Aim. The most frequent method for the assessment of glomerular filtration rate GFR) in clinical practice is clearance of creatinine, clearance of chromium-51 radiolabelled ethylene diamine tetraacetic acid (51Cr-EDTA) and clearance of ...
Dopuđa Marija   +4 more
doaj   +1 more source

Mitochondrial Dyshomeostasis as an Early Hallmark and a Therapeutic Target in Amyotrophic Lateral Sclerosis

open access: yesInternational Journal of Molecular Sciences, 2023
Amyotrophic lateral sclerosis (ALS) is a fatal multisystem disease characterized by progressive death of motor neurons, loss of muscle mass, and impaired energy metabolism.
N. Belosludtseva   +2 more
semanticscholar   +1 more source

Research on matching of 102-type coupler with secondary suspension parameters of heavy-haul locomotives

open access: yes机车电传动, 2023
The secondary suspension parameters of locomotives have a significant influence on the stability of heavy-haul couplers under compression. This paper aimed to explore the reasonable matching between 102-type couplers and the secondary suspension ...
MA Qun   +4 more
doaj  

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