Results 41 to 50 of about 667,708 (253)

Integrating a Water Tracer Model Into WRF‐Hydro for Characterizing the Effect of Lateral Flow in Hydrologic Simulations

Water Resources Research
Most current land models approximate terrestrial hydrological processes as one‐dimensional vertical flow, neglecting lateral water movement from ridges to valleys.
Huancui Hu, L. Ruby Leung, Francina Dominguez, David Gochis, Xingyuan Chen, Stephen Good, Aubrey Dugger, Laurel Larsen, Michael Barlage   +8 more
doaj   +1 more source

Rapid Detection of Alpha-Fetoprotein (AFP) with Lateral Flow Aptasensor

Molecules
We present a lateral flow aptasensor for the visual detection of alpha-fetoprotein (AFP) in human serum. Leveraging the precise molecular recognition capabilities of aptamers and the distinct optical features of gold nanoparticles, a model system ...
Meijing Ma, Min Zhang, Jiahui Wang, Yurui Zhou, Xueji Zhang, Guodong Liu   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Rapid and sensitive diagnosis of live Mycobacterium tuberculosis using clustered regularly interspaced short palindromic repeat‐Cas13a point‐of‐care RNA testing

View
Mycobacterium tuberculosis (MTB) is the causal pathogen of tuberculosis (TB). Rapid and accurate detection of live MTB is important for transmission control and patient treatment.
Yu Wang, Huihuang Lin, Anqi Yang, Jiaming Huang, Weicong Ren, Jiajun Dong, Shaojie Wang, Wenxue Xu, Yu Pang, Jieming Qu, Jia Liu   +10 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Development of an indirect enzyme-linked immunosorbent assay and lateral-flow test strips for pefloxacin and its analogues in chicken muscle samples

Food and Agricultural Immunology, 2018
An anti-pefloxacin (PEF) monoclonal antibody (mAb), an indirect competitive enzyme-linked immunosorbent assay and lateral-flow test strip methods were developed to detect fluoroquinolone (FQ) residues in chicken muscle samples. Under optimised conditions,
Daniel Mukunzi, Steven Suryoprabowo, Shanshan Song, Liqiang Liu, Hua Kuang   +4 more
doaj   +1 more source

Map estimation of air-flow dipole source positions using array signal processing [PDF]

, 2010
In nature, fish have the ability to form flow-based maps to assist localizing predator or prey using the lateral-line system. Yet it is not fully understood what techniques are used by fish to draw these flow maps.
Dagamseh, A.M.K., Krijnen, G.J.M.
core   +1 more source

An analysis of the far-field response to external forcing of a suspension in Stokes flow in a parallel-wall channel

, 2008
The leading-order far-field scattered flow produced by a particle in a parallel-wall channel under creeping flow conditions has a form of the parabolic velocity field driven by a 2D dipolar pressure distribution.
Cichocki B., E. Wajnryb, Edmonds A. R., Frenkel D., J. Bławzdziewicz, Jackson W. D., Kim S., Shankar R.   +7 more
core   +1 more source

Pairwise hydrodynamic interactions and diffusion in a vesicle suspension [PDF]

, 2014
The hydrodynamic interaction of two deformable vesicles in shear flow induces a net displacement, in most cases an increase of their distance in the transverse direction.
Coupier, Gwennou, Gires, Pierre-Yves, Misbah, Chaouqi, Podgorski, Thomas, Srivastav, Aparna   +4 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source