Results 31 to 40 of about 102,661 (259)

Rapid Diagnostic Technique for Rabies Virus Detection

open access: yesJournal of Medical Microbiology and Infectious Diseases, 2023
Precise diagnosis is crucial for implementing suitable and timely treatment strategies, especially when dealing with life-threatening infections like rabies.
Farzaneh Sheikholeslami1*
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Triple-Mode Lateral Flow Assay Biosensor For Periodontal Detect

open access: yesInternational Dental Journal
Aim or purpose: This triple-mode biosensor aimed to simplify detection, reduce false positives, and enhance signal strength while optimizing the balance between detection sensitivity and range in a solid-state sensor. Effectively identified periodontitis
Chen Cong
doaj   +1 more source

453 Rapid SARS-CoV-2 testing with duplexed recombinase polymerase amplification and a bacteriophage internal control

open access: yesJournal of Clinical and Translational Science, 2023
OBJECTIVES/GOALS: Current COVID-19 rapid molecular tests require cartridge-reader detection, expensive circuitry, and complex microfluidics making the most accurate tests unavailable to the masses.
Coleman Martin   +5 more
doaj   +1 more source

Lateral-flow assays for bovine paratuberculosis diagnosis

open access: yesFrontiers in Veterinary Science, 2023
Mycobacterium avium subsp. paratuberculosis (MAP) causes bovine paratuberculosis (PTB). PTB is responsible for significant economic losses in dairy herds around the word. PTB control programs that rely on testing and culling of test-positive cows have been developed.
Marta Alonso-Hearn   +4 more
openaire   +3 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Amplifying Lateral Flow Assay Signals for Rapid Detection of COVID‐19 Specific Antibodies

open access: yesGlobal Challenges, 2022
Rapid lateral flow immune‐assays are point‐of‐care diagnostic tools that are easy to use, cheap, and do not need centralized infrastructure. Therefore, these devices are appealing for rapid detection of the humoral immune responses to infections ...
Rowa Y. Alhabbab   +7 more
doaj   +1 more source

Lateral flow assay for detection and recovery of live cell Neisseria gonorrhoeae

open access: yesCurrent Research in Biotechnology, 2022
Gonorrhea, caused by Neisseria gonorrhoeae, is a global disease that disproportionately impacts low- and middle-income countries. Current testing methods have failed to significantly reduce disease burden, thereby allowing untreated gonorrhea infections ...
Taylor Oeschger   +2 more
doaj   +1 more source

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