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2016
A typical lateral flow biosensor employs a sandwich detection system and uses tracer(s) to generate detectable signal(s) (Figure 13.1). However, recent advances in nanomaterials offer a wide variety of improvement options, including new detection methodologies, signal transformation and improvements in sensitivity and specificity [4-6]. In this chapter,
Li, Jia, Macdonald, J
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A typical lateral flow biosensor employs a sandwich detection system and uses tracer(s) to generate detectable signal(s) (Figure 13.1). However, recent advances in nanomaterials offer a wide variety of improvement options, including new detection methodologies, signal transformation and improvements in sensitivity and specificity [4-6]. In this chapter,
Li, Jia, Macdonald, J
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Paper-Based Biosensors with Lateral/Vertical Flow Assay
2020The lateral flow assay (LFA), which is a simple paper-based device for the detection and analysis of disease, is now the most predominant diagnostic platform in point-of-care (POC) markets [1, 2, 3, 4]. This market-dominating power stems from the unique characteristics of the LFA: low cost, portability, versatility, easy use, free of other instruments,
Dohwan Lee, Jeong Hoon Lee
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Analytical Biochemistry, 2021
MicroRNAs (miRNAs) are short RNA sequences found in eukaryotic cells and they are involved in several diseases pathogenesis including different types of cancers, metabolic and cardiovascular disorders. Thus, miRNAs circulating in serum, plasma, and other body fluids are employed as biomarkers for diagnostic and prognostic purposes and in assessment of ...
Niloofar, Khandan-Nasab +5 more
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MicroRNAs (miRNAs) are short RNA sequences found in eukaryotic cells and they are involved in several diseases pathogenesis including different types of cancers, metabolic and cardiovascular disorders. Thus, miRNAs circulating in serum, plasma, and other body fluids are employed as biomarkers for diagnostic and prognostic purposes and in assessment of ...
Niloofar, Khandan-Nasab +5 more
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IEEE Transactions on NanoBioscience, 2023
Methamphetamine is a powerful stimulant drug, the abuse of which threatens human health and social stability. Rapid and accurate quantification of methamphetamine is essential to inhibit the abuse and prevalence of methamphetamine effectively. In this paper, we present a portable fluorescence reader with upconverting nanoparticle-labeled lateral flow ...
Lei Huang +5 more
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Methamphetamine is a powerful stimulant drug, the abuse of which threatens human health and social stability. Rapid and accurate quantification of methamphetamine is essential to inhibit the abuse and prevalence of methamphetamine effectively. In this paper, we present a portable fluorescence reader with upconverting nanoparticle-labeled lateral flow ...
Lei Huang +5 more
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Lateral Flow Biosensors for the Detection of Nucleic Acid
2013The detection of nucleic acid is of central importance for the diagnosis of genetic diseases, infectious agents, and biowarfare agents. Traditional strategies and technologies for nucleic acid detection are time-consuming and labor-intensive. Recently, isothermal strand-displacement reaction-based lateral flow biosensors have attracted a great deal of ...
Lingwen, Zeng +3 more
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Biosensors and Bioelectronics, 2011
In this article, we describe an ultrasensitive nucleic acid biosensor (NAB) based on horseradish peroxidase (HRP)-gold nanoparticle (Au-NP) dual labels and lateral flow strip biosensor (LFSB). The results presented here expand on prior work (Mao et al., 2009a) by optimizing the preparation of HRP-Au-NP-DNA conjugates.
Yuqing, He +7 more
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In this article, we describe an ultrasensitive nucleic acid biosensor (NAB) based on horseradish peroxidase (HRP)-gold nanoparticle (Au-NP) dual labels and lateral flow strip biosensor (LFSB). The results presented here expand on prior work (Mao et al., 2009a) by optimizing the preparation of HRP-Au-NP-DNA conjugates.
Yuqing, He +7 more
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Nanolabels for biosensors based on lateral flow immunoassays
Analytica Chimica ActaThe COVID-19 outbreak was an important turning point in the development of a new generation of biosensing technologies. The synergistic combination of an immunochromatographic test (lateral flow immunoassays, LFIA) and signal transducers provides enhanced sensitivity and the ability to quantify in the rapid tests. This is possible due to the variety of
C. Saweres-Argüelles +4 more
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Lateral Flow Biosensors Based on Gold Nanoparticles
2014Abstract The aim of these authors is to offer to the reader the general basis of lateral flow technology and overall of that based on the use of gold nanoparticles, its design, and various useful analytical applications. The historical progress of this technology discussed first is followed by a detailed description of the basic principles, formats ...
Lourdes Rivas +3 more
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A lateral flow biosensor for rapid detection of Singapore grouper iridovirus (SGIV)
Aquaculture, 2021Abstract Iridoviruses are well-known as causative agents of serious systemic diseases, and have been identified in more than 100 fish species worldwide in the last few decades. Singapore grouper iridovirus (SGIV) is a devastating viral pathogen of grouper aquaculture, and has caused substantial economic losses in China and Southeast Asia.
Jiaxin Liu +8 more
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A lateral flow biosensor for the detection of human pluripotent stem cells
Analytical Biochemistry, 2013A lateral flow biosensor based on immunoassay has been developed for the detection of human stem cells for the first time. Antibody specific for a human stem cell surface antigen, SSEA-4, is coated onto gold nanoparticles, whereas antibody against another human pluripotent stem cell surface antigen, SSEA-3, is immobilized on the test zone of the NC ...
Wei, Wu +4 more
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