Results 41 to 50 of about 219,064 (327)

Potential of activated microglia as a source of dysregulated extracellular microRNAs contributing to neurodegeneration in amyotrophic lateral sclerosis [PDF]

open access: yes, 2020
Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron degeneration in adults, and several mechanisms underlying the disease pathology have been proposed.
Christoforidou, Eleni   +2 more
core   +1 more source

Horizontal gene transfer is not a hallmark of the human genome

open access: yesGenome Biology, 2017
Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al.
Steven L. Salzberg
doaj   +1 more source

The Xylella fastidosa RTX operons: evidence for the evolution of protein mosaics through novel genetic exchanges

open access: yesBMC Genomics, 2018
Background Xylella fastidiosa (Xf) is a gram negative bacterium inhabiting the plant vascular system. In most species this bacterium lives as a benign symbiote, but in several agriculturally important plants (e.g.
Gregory A. Gambetta   +2 more
doaj   +1 more source

Unconventional lateral gene transfer in extreme thermophilic bacteria. [PDF]

open access: yes, 2016
Conjugation and natural competence are two major mechanisms that explain the acquisition of foreign genes throughout bacterial evolution. In recent decades, several studies in model organisms have revealed in great detail the steps involved in such ...
Berenguer, José   +4 more
core   +1 more source

Lateral gene transfer in the subsurface [PDF]

open access: yes, 2007
Lateral gene transfer (LGT) is an important adaptive mechanism among prokaryotic organisms. This mechanism is particularly important for the response of microorganisms to changing environmental conditions because it facilitates the transfer of a large number of genes and their rapid expression.
Barkay, Tamar, Sobecky, Patricia
openaire   +3 more sources

A Bayesian Method for Analyzing Lateral Gene Transfer [PDF]

open access: yesSystematic Biology, 2014
Lateral gene transfer (LGT)--which transfers DNA between two non-vertically related individuals belonging to the same or different species--is recognized as a major force in prokaryotic evolution, and evidence of its impact on eukaryotic evolution is ever increasing.
Lars Arvestad   +9 more
openaire   +3 more sources

CRISPR loci reveal networks of gene exchange in archaea

open access: yesBiology Direct, 2011
Background CRISPR (Clustered, Regularly, Interspaced, Short, Palindromic Repeats) loci provide prokaryotes with an adaptive immunity against viruses and other mobile genetic elements.
Brodt Avital   +2 more
doaj   +1 more source

Evidence for the intense exchange of MazG in marine cyanophages by horizontal gene transfer [PDF]

open access: yes, 2008
Background: S-PM2 is a phage capable of infecting strains of unicellular cyanobacteria belonging to the genus Synechococcus. S-PM2, like other myoviruses infecting marine cyanobacteria, encodes a number of bacterial-like genes. Amongst these genes is one
Bryan, Michael J.   +5 more
core   +3 more sources

Within-species lateral genetic transfer and the evolution of transcriptional regulation in Escherichia coli and Shigella

open access: yesBMC Genomics, 2011
Background Changes in transcriptional regulation underlie many of the phenotypic differences observed within and between species of bacteria. Lateral genetic transfer (LGT) can significantly impact the transcription factor (TF) genes which drive these ...
Ragan Mark A, Skippington Elizabeth
doaj   +1 more source

The Carbapenemase BKC-1 from Klebsiella pneumoniae Is Adapted for Translocation by Both the Tat and Sec Translocons

open access: yesmBio, 2021
Bacteria can readily acquire plasmids via lateral gene transfer (LGT). These plasmids can carry genes for virulence and antimicrobial resistance (AMR).
Manasa Bharathwaj   +5 more
doaj   +1 more source

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