Results 41 to 50 of about 219,064 (327)
Potential of activated microglia as a source of dysregulated extracellular microRNAs contributing to neurodegeneration in amyotrophic lateral sclerosis [PDF]
Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron degeneration in adults, and several mechanisms underlying the disease pathology have been proposed.
Christoforidou, Eleni+2 more
core +1 more source
Horizontal gene transfer is not a hallmark of the human genome
Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al.
Steven L. Salzberg
doaj +1 more source
Background Xylella fastidiosa (Xf) is a gram negative bacterium inhabiting the plant vascular system. In most species this bacterium lives as a benign symbiote, but in several agriculturally important plants (e.g.
Gregory A. Gambetta+2 more
doaj +1 more source
Unconventional lateral gene transfer in extreme thermophilic bacteria. [PDF]
Conjugation and natural competence are two major mechanisms that explain the acquisition of foreign genes throughout bacterial evolution. In recent decades, several studies in model organisms have revealed in great detail the steps involved in such ...
Berenguer, José+4 more
core +1 more source
Lateral gene transfer in the subsurface [PDF]
Lateral gene transfer (LGT) is an important adaptive mechanism among prokaryotic organisms. This mechanism is particularly important for the response of microorganisms to changing environmental conditions because it facilitates the transfer of a large number of genes and their rapid expression.
Barkay, Tamar, Sobecky, Patricia
openaire +3 more sources
A Bayesian Method for Analyzing Lateral Gene Transfer [PDF]
Lateral gene transfer (LGT)--which transfers DNA between two non-vertically related individuals belonging to the same or different species--is recognized as a major force in prokaryotic evolution, and evidence of its impact on eukaryotic evolution is ever increasing.
Lars Arvestad+9 more
openaire +3 more sources
CRISPR loci reveal networks of gene exchange in archaea
Background CRISPR (Clustered, Regularly, Interspaced, Short, Palindromic Repeats) loci provide prokaryotes with an adaptive immunity against viruses and other mobile genetic elements.
Brodt Avital+2 more
doaj +1 more source
Evidence for the intense exchange of MazG in marine cyanophages by horizontal gene transfer [PDF]
Background: S-PM2 is a phage capable of infecting strains of unicellular cyanobacteria belonging to the genus Synechococcus. S-PM2, like other myoviruses infecting marine cyanobacteria, encodes a number of bacterial-like genes. Amongst these genes is one
Bryan, Michael J.+5 more
core +3 more sources
Background Changes in transcriptional regulation underlie many of the phenotypic differences observed within and between species of bacteria. Lateral genetic transfer (LGT) can significantly impact the transcription factor (TF) genes which drive these ...
Ragan Mark A, Skippington Elizabeth
doaj +1 more source
Bacteria can readily acquire plasmids via lateral gene transfer (LGT). These plasmids can carry genes for virulence and antimicrobial resistance (AMR).
Manasa Bharathwaj+5 more
doaj +1 more source