Results 51 to 60 of about 230,314 (320)

In vivo genetic manipulation of inner ear connexin expression by bovine adeno-Associated viral vectors [PDF]

, 2017
We have previously shown that in vitro transduction with bovine adeno-associated viral (BAAV) vectors restores connexin expression and rescues gap junction coupling in cochlear organotypic cultures from connexin-deficient mice that are models DFNB1 ...
Campioni, Matteo, Chiorini, John A., Crispino, Giulia, Di Pasquale, Giovanni, Galindo Ramirez, Fabian, Mammano, Fabio, Praetorius, Mark, Zorzi, Veronica   +7 more
core   +1 more source

Characterizing Scales of Genetic Recombination and Antibiotic Resistance in Pathogenic Bacteria Using Topological Data Analysis

, 2014
Pathogenic bacteria present a large disease burden on human health. Control of these pathogens is hampered by rampant lateral gene transfer, whereby pathogenic strains may acquire genes conferring resistance to common antibiotics. Here we introduce tools
A. Holzinger, C. Fraser, C.M. Thomas, C.R. Woese, F. Meyer, G. Carlsson, H. Ochman, H. Rohde, H.C. Neu, J.E. Cooper, J.M. Chan, K.A. Jolley, M.O. Sommer, T. Dagan   +13 more
core   +1 more source

Horizontal gene transfer contributes to plant evolution : the case of Agrobacterium T-DNAs [PDF]

, 2017
Horizontal gene transfer (HGT) can be defined as the acquisition of genetic material from another organism without being its offspring. HGT is common in the microbial world including archaea and bacteria, where HGT mechanisms are widely understood and ...
Gheysen, Godelieve, Kreuze, Jan F, Quispe Huamanquispe, Dora   +2 more
core   +1 more source

Lateral Transfer of Genes and Gene Fragments in Prokaryotes [PDF]

Genome Biology and Evolution, 2009
Lateral genetic transfer (LGT) involves the movement of genetic material from one lineage into another and its subsequent incorporation into the new host genome via genetic recombination. Studies in individual taxa have indicated lateral origins for stretches of DNA of greatly varying length, from a few nucleotides to chromosome size. Here we analyze 1,
Chan, Cheong Xin, Beiko, Robert G., Darling, Aaron E., Ragan, Mark A.   +3 more
openaire   +3 more sources

Adapting for life in the extreme

eLife, 2019
Red algae have adapted to extreme environments by acquiring genes from bacteria and archaea.
Carolin M Kobras, Daniel Falush
doaj   +1 more source

GOLVEN peptide signalling through RGI receptors and MPK6 restricts asymmetric cell division during lateral root initiation [PDF]

, 2020
During lateral root initiation, lateral root founder cells undergo asymmetric cell divisions that generate daughter cells with different sizes and fates, a prerequisite for correct primordium organogenesis.
Alves Neubus Claus, Lucas, Beeckman, Tom, De Gernier, dr. Hugues, Drozdzecki, Andrzej, Fernandez Salina, Ana, Hoogewijs, Kurt, Jourquin, Joris, Madder, Annemieke, Maruta, Takanori, Morales, Stefania, Nimchuk, Zachary L., Opdenacker, Davy, Parizot, Boris, Peterson, Brenda, Russinova, Eugenia, Vangheluwe, Nick, Vannecke, Willem, Xu, Ke, Yu, Qiaozhi   +18 more
core   +1 more source

The genomes of polyextremophilic cyanidiales contain 1% horizontally transferred genes with diverse adaptive functions

eLife, 2019
The role and extent of horizontal gene transfer (HGT) in eukaryotes are hotly disputed topics that impact our understanding of the origin of metabolic processes and the role of organelles in cellular evolution.
Alessandro W Rossoni, Dana C Price, Mark Seger, Dagmar Lyska, Peter Lammers, Debashish Bhattacharya, Andreas PM Weber   +6 more
doaj   +1 more source

Pattern formation during de novo assembly of the Arabidopsis shoot meristem [PDF]

, 2007
Most multicellular organisms have a capacity to regenerate tissue after wounding. Few, however, have the ability to regenerate an entire new body from adult tissue. Induction of new shoot meristems from cultured root explants is a widely used, but poorly
Das, Pradeep, Gordon, Sean P., Heisler, Marcus G., Meyerowitz, Elliot M., Ohno, Carolyn, Reddy, G. Venugopala   +5 more
core   +2 more sources

Evolution of glutamate dehydrogenase genes: evidence for lateral gene transfer within and between prokaryotes and eukaryotes

BMC Evolutionary Biology, 2003
Background Lateral gene transfer can introduce genes with novel functions into genomes or replace genes with functionally similar orthologs or paralogs. Here we present a study of the occurrence of the latter gene replacement phenomenon in the four gene ...
Roger Andrew J, Andersson Jan O
doaj   +1 more source

Of woods and webs: possible alternatives to the tree of life for studying genomic fluidity in E. coli

Biology Direct, 2011
Background We introduce several forest-based and network-based methods for exploring microbial evolution, and apply them to the study of thousands of genes from 30 strains of E. coli.
Lapointe François-Joseph, Lopez Philippe, Schliep Klaus, Bicep Cédric, Beauregard-Racine Julie, Bapteste Eric   +5 more
doaj   +1 more source