Results 41 to 50 of about 72,818 (259)

Comparison of the Flow Fields between Nozzles with Full-Open and Open-Close Valves at Transonic Velocity

open access: yesJournal of Applied Mathematics, 2022
At transonic velocity, ejector nozzles require third auxiliary intake valves to increase air intake, resulting in good thrust performance. However, different intake structures will inevitably lead to different internal flow-field structures and thrust ...
Zijie Li, Hao Wang
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Manipulations of attention during eating and their effects on later snack intake [PDF]

open access: yesAppetite, 2015
Manipulation of attention during eating has been reported to affect later consumption via changes in meal memory. The aim of the present studies was to examine the robustness of these effects and investigate moderating factors. Across three studies, attention to eating was manipulated via distraction (via a computer game or TV watching) or focusing of ...
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

UJI MODEL FISIK PENGENDALIAN ELEVASI DASAR SUNGAI DI SEKITAR INTAKE POLDER ALABIO, KABUPATEN HULU SUNGAI UTARA, PROPINSI KALIMANTAN TIMUR DENGAN MENGGUNAKAN VANE

open access: yesJurnal Teknik Sipil, 2021
Pada makalah ini disampaikan hasil penelitian terhadap pengendalian elevasi dasar sungai di depan intake dengan menggunakan vane, pada kasus intake Irigasi Polder Alabio, Kabupaten Hulu Sungai Utara, Propinsi Kalimantan Selatan, dengan menggunakan model
Joko Nugroho   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Milk Intake in Early Life and Later Cancer Risk: A Meta-Analysis

open access: yesNutrients, 2022
Dairy consumption in adulthood has been demonstrated to influence cancer risk. Although childhood and adolescence represent critical periods of rapid growth, the relationship between milk intake in early life and later cancer risk is unclear. Thus, we examined this relationship by conducting a meta-analysis of the observational studies.
Hyeonmin Gil   +6 more
openaire   +2 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Hydrodynamic characteristics and particle tracking of 90° lateral intakes at an inclined river slope

open access: yesWater Science and Engineering
Lateral intakes are common in rivers. The pump efficiency and sediment deposition are determined by the local hydrodynamic characteristics and mainstream division width.
Wei He   +6 more
doaj   +1 more source

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