Results 21 to 30 of about 5,452,270 (287)

Neural stem cells induce the formation of their physical niche during organogenesis

open access: yeseLife, 2017
Most organs rely on stem cells to maintain homeostasis during post-embryonic life. Typically, stem cells of independent lineages work coordinately within mature organs to ensure proper ratios of cell types.
Ali Seleit   +7 more
doaj   +1 more source

The Cholinergic Lateral Line Efferent Synapse: Structural, Functional and Molecular Similarities With Those of the Cochlea

open access: yesFrontiers in Cellular Neuroscience, 2021
Vertebrate hair cell (HC) systems are innervated by efferent fibers that modulate their response to external stimuli. In mammals, the best studied efferent-HC synapse, the cholinergic medial olivocochlear (MOC) efferent system, makes direct synaptic ...
Paola V. Plazas, Ana Belén Elgoyhen
doaj   +1 more source

The valvula cerebelli of the spiny eel, Macrognathus aculeatus, receives primary lateral-line afferents from the rostrum of the upper jaw [PDF]

open access: yes, 1991
In the spiny eel, Macrognathus aculeatus, anterodorsal and (to a lesser degree) anteroventral lateralline nerves project massively to the granular layer of the valvula cerebelli, throughout its rostrocaudal extent.
Wullimann, M.   +5 more
core   +1 more source

Cumulative mitochondrial activity correlates with ototoxin susceptibility in zebrafish mechanosensory hair cells

open access: yeseLife, 2018
Mitochondria play a prominent role in mechanosensory hair cell damage and death. Although hair cells are thought to be energetically demanding cells, how mitochondria respond to these demands and how this might relate to cell death is largely unexplored.
Sarah B Pickett   +6 more
doaj   +1 more source

Chronic neurotransmission increases the susceptibility of lateral-line hair cells to ototoxic insults

open access: yeseLife, 2022
Sensory hair cells receive near constant stimulation by omnipresent auditory and vestibular stimuli. To detect and encode these stimuli, hair cells require steady ATP production, which can be accompanied by a buildup of mitochondrial byproducts called ...
Daria Lukasz, Alisha Beirl, Katie Kindt
doaj   +1 more source

Reaction–Diffusion Finite Element Model of Lateral Line Primordium Migration to Explore Cell Leadership [PDF]

open access: yes, 2014
Collective cell migration plays a fundamental role in many biological phenomena such as immune response, embryogenesis and tumorigenesis. In the present work, we propose a reaction–diffusion finite element model of the lateral line primordium migration ...
Maini, P K   +3 more
core   +1 more source

Farmed Salmon Show No Pathological Alterations When Exposed to Acoustic Treatment for Sea Lice Infestation

open access: yesJournal of Marine Science and Engineering, 2021
The use of bioacoustic methods to address sea lice infestation in salmonid farming is a promising innovative method but implies an exposure to sound that could affect the fish.
Marta Solé   +6 more
doaj   +1 more source

Using the Zebrafish Lateral Line to Understand the Roles of Mitochondria in Sensorineural Hearing Loss

open access: yesFrontiers in Cell and Developmental Biology, 2021
Hair cells are the mechanosensory receptors of the inner ear and can be damaged by noise, aging, and ototoxic drugs. This damage often results in permanent sensorineural hearing loss.
Melanie Holmgren   +2 more
doaj   +1 more source

Lpar2b Controls Lateral Line Tissue Size by Regulating Yap1 Activity in Zebrafish

open access: yesFrontiers in Molecular Neuroscience, 2018
LPA signaling plays important roles during cell migration and proliferation in normal and pathological conditions. However, its role during sensory organ development remains unknown.
Xueqian Wang   +10 more
doaj   +1 more source

Emx2 regulates hair cell rearrangement but not positional identity within neuromasts

open access: yeseLife, 2020
Each hair cell (HC) precursor of zebrafish neuromasts divides to form two daughter HCs of opposite hair bundle orientations. Previously, we showed that transcription factor Emx2, expressed in only one of the daughter HCs, generates this bidirectional HC ...
Sho Ohta   +3 more
doaj   +1 more source

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