Results 71 to 80 of about 5,030,269 (303)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Integrated Adaptive Cruise Control with Weight Coefficient Self-Tuning Strategy

open access: yesApplied Sciences, 2018
This paper presents a novel multi-objective coordinated adaptive cruise control (ACC) algorithm based on a model predictive control (MPC) framework which can comprehensively address issues regarding longitudinal car-following performance, lateral ...
Junhui Zhang, Qing Li, Dapeng Chen
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Adaptive Coordinated Trajectory Tracking and Yaw Stability Control for 4WID Electric Vehicles

open access: yesWorld Electric Vehicle Journal
Achieving simultaneous trajectory accuracy and dynamic stability is challenging for four-wheel independent drive (4WID) electric vehicles under near-limit conditions.
Gang Liu   +4 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Lateral Vibrations as Related to Structural Stability [PDF]

open access: yesJournal of Applied Mechanics, 1952
Abstract The apparently different physical problems of lateral vibration and elastic stability are limiting cases of a single phenomenon, the more general expression being the mode of vibration with end thrust. It is shown that the square of the frequency of lateral vibration is approximately linearly related to the end load.
openaire   +2 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Analysis of characteristics of lateral stability of sailplane Lak 17a by computational method

open access: yesMokslas: Lietuvos Ateitis, 2011
A computer-based geometrical model of the Lak-17a sailplane was generated with the program AVL (Athena Vortex Lattice), which is designed to analyse the characteristics of flight and to provide a rapid analysis of the configuration of an aircraft ...
Paulius Gildutis, Eduardas Lasauskas
doaj   +1 more source

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